Study of the Prevalence of Osteo-metabolic Complications in Patients With Thyroid Cancer
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 82
- 试验地点
- 1
- 主要终点
- To estimate the incidence and prevalence of osteoporosis and vertebral fractures in Patients With Thyroid Cancer
研究概览
简要总结
This is a multicenter retrospective observational study aimed to evaluate the prevalence of osteo-metabolic complications in patients with thyroid cancer.
详细描述
Approximately 150-200 outpatients evaluated in the Endocrinology Unit of the IRCCS San Raffaele Hospital and the Nuclear Medicine Unit of the Spedali Civili of Brescia will be included in the study.
During the follow-up visits, patients who meet the inclusion criteria will be offered inclusion in the study. After signing the informed consent, the patient's anamnestic and clinical (biochemical, radiological, anamnestic) data will be retrospectively collected in an electronic database. Sensitive data will be anonymized.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •age ≥ 18 years
- •Histological diagnosis of Thyroid Carcinoma
- •radiological data from chest x-ray in lateral projection in the preoperative evaluation on which the vertebral morphometry
- •Signing of the informed consent
排除标准
- •Subjects not falling within the previously described criteria are excluded
结局指标
主要结局
To estimate the incidence and prevalence of osteoporosis and vertebral fractures in Patients With Thyroid Cancer
时间窗: 1 year
To estimate the incidence and prevalence of osteoporosis and vertebral fractures detected through DXA scan and vertebral morphometry. The effects on bone complications of the patients' clinical and biochemical characteristics will be investigated.
次要结局
未报告次要终点
研究者
Andrea Giustina
Professor of Endocrinology
IRCCS San Raffaele