Investigation of an artificial pancreas for adults with type 1 diabetes
Not Applicable
Completed
- Conditions
- Metabolic and Endocrine - DiabetesType 1 diabetes mellitus
- Registration Number
- ACTRN12617000520336
- Lead Sponsor
- The University of Melbourne
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 150
Inclusion Criteria
1. Type 1 diabetes
2. Insulin delivered via either multiple daily (basal and bolus) injections, or via insulin pump (for at least 3 months)
3. HbA1c <= 10.5%
Exclusion Criteria
1.Chronic kidney disease (eGFR <45mL/min/1.73m2)
2.Current use of real-time CGM
3.Use of non-insulin glucose-lowering agent in the past 3 months
4.Steroid use (oral or injected) within past 3 months
5.Pregnancy
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Percent of time CGM sensor glucose is in target range (3.9-10 mmol/L) during HCL vs standard therapy.<br>[End-of-study (23 - 26 weeks post-randomisation)]
- Secondary Outcome Measures
Name Time Method