jRCT2041250143
Recruiting
Not Applicable
A PHASE IIb, MULTICENTER, DOUBLE-BLIND, PLACEBO-CONTROLLED INDUCTION STUDY WITH AN ACTIVE TREATMENT EXTENSION TO ASSESS THE EFFICACY, SAFETY, AND PHARMACOKINETICS OF RO7837195 IN PATIENTS WITH MODERATELY TO SEVERELY ACTIVE ULCERATIVE COLITIS
Not provided0 sites17 target enrollmentStarted: TBD
ConditionsUlcerative Colitis
Overview
- Phase
- Not Applicable
- Status
- Recruiting
- Enrollment
- 17
Overview
Brief Summary
No summary available.
Study Design
- Study Type
- Interventional
- Allocation
- Randomized
Eligibility Criteria
- Ages
- 18age old over to No limit (—)
- Sex
- All
Inclusion Criteria
- •Diagnosis of ulcerative colitis (UC) established at least 3 months
- •Moderately to severely active UC assessed by mMS
- •Inadequate response, loss of response, or intolerance to conventional or advanced therapies for UC
Exclusion Criteria
- •Prior extensive colonic resection, subtotal or total colectomy, or planned surgery for UC
- •Diagnosis of Crohn's disease or indeterminate colitis
- •Treatment with an advanced therapy targeted at tumor necrosis factor-like cytokine 1A (TL1a)
- •Inadequate response, loss of response, or intolerance to treatment of UC with an advanced therapy targeted at IL-12 and/or IL-23
Investigators
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