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临床试验/NCT07663019
NCT07663019招募中不适用

Effects of a Chatbot-Based Intervention on Valence-Dependent Belief Updating and Expectancy Bias for Life Events in Individuals With Anhedonia

University of Electronic Science and Technology of China1 个研究点 分布在 1 个国家目标入组 80 人开始时间: 2026年6月20日最近更新:
适应症
干预措施

试验速览

阶段
不适用
状态
招募中
发起方
入组人数
80
试验地点
1

研究概览

简要总结

The main aim of the present study is to investigate the effects of a Motivational Interviewing-based artificial intelligence chatbot on belief updating in college students with elevated levels of depression and anhedonia by combining a randomized active-control intervention design with pre- and post-intervention behavioral belief updating task assessments.

详细描述

Anhedonia represents a core characteristic of depression and is characterized by reduced experience of pleasure. It is closely related to decreased motivation, altered reward processing, changes in affective responsiveness, and alterations in intrinsic brain network function. Anhedonia is not specifically targeted by currently available pharmacological interventions. Initial evidence indicates that an increased willingness to change and implementation of change in daily life can alleviate anhedonia.

The present study aims to examine whether a Motivational Interviewing-based AI chatbot can lead to changes in belief updating in college students with elevated anhedonia and depressive symptoms. Belief updating is included because anhedonia and depressive symptoms may be associated with biased or inflexible use of new information, which may influence future expectations, motivation, and engagement in rewarding activities. The belief updating task allows the study to examine how participants revise their expectations after receiving new information. To this end, eligible participants with a total score of 22 or higher on the Snaith-Hamilton Pleasure Scale and a score of 14 or higher on the Beck Depression Inventory will undergo a randomized, between-subjects, active-control intervention study. Participants will be assigned to either a Motivational Interviewing-based chatbot group or an active control chatbot group for 1 week. Pre- and post-intervention assessments will include self-report questionnaires and a behavioral belief updating task to examine psychological and behavioral effects of the intervention.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Basic Science
盲法
Double (Participant, Investigator)

入排标准

年龄范围
18 Years 至 40 Years(Adult)
性别
All
接受健康志愿者

入选标准

  • 18-40 years
  • Right-handed
  • Normal or corrected normal visual acuity
  • Participants must show elevated anhedonia and depressive symptoms at screening, defined as a total score of 22 or higher on the Snaith-Hamilton Pleasure Scale and a score of 14 or higher on the Beck Depression Inventory

排除标准

  • History of major central nervous system disorders, such as epilepsy, traumatic brain injury, stroke, or brain tumors.
  • History of severe mental illness, including schizophrenia spectrum disorders, bipolar disorder, or other psychotic disorders.
  • History of substance or alcohol use disorder or substance or alcohol misuse within the past 12 months that may affect study participation or outcome assessment.
  • Individuals currently at high risk of suicide, severe self-harm, or experiencing an acute psychiatric crisis.
  • Individuals who are currently using psychiatric medications or have undergone psychotherapy within the past 4 weeks that may significantly affect mood, motivation, or reward processing.
  • Severe vision or hearing impairments that cannot be corrected and would interfere with task performance.
  • Contraindications to MRI scanning, including metallic implants, pacemakers, severe claustrophobia, or other conditions incompatible with MRI.
  • Pregnancy or breastfeeding.

研究组 & 干预措施

Motivational Interviewing-based AI chatbot group

Experimental

Motivational Interviewing-based AI chatbot intervention

干预措施: MI Chatbot Interaction (Behavioral)

Active control chatbot group

Active Comparator

Active control nature-story chatbot intervention

干预措施: Active Control Chatbot Interaction (Behavioral)

研究者

发起方
University of Electronic Science and Technology of China
申办方类型
Other
责任方
Principal Investigator
主要研究者

Benjamin Becker

Professor

University of Electronic Science and Technology of China

研究点 (1)

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