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临床试验/NCT06102668
NCT06102668已完成不适用

Long-term Survival and Parenteral Nutrition Dependence in Adult Patients With Non-malignant Short Bowel Syndrome

The First Affiliated Hospital of University of Science and Technology of China0 个研究点目标入组 173 人开始时间: 2012年1月1日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
173
主要终点
Survival

研究概览

简要总结

Short bowel syndrome (SBS) is a rare condition resulting from the loss of portions of the small intestine, and can cause a spectrum of metabolic and physiologic disturbances.The objective of this study was to determine the longterm survival and parenteral nutrition dependence of adult patients with SBS.

详细描述

Short bowel syndrome (SBS), the most common form of intestinal failure, is a rare condition resulting from the loss of portions of the intestine, typically because of extensive surgical resection or loss of intestinal function. Patients with SBS often stuffer from intestinal insufficiency or intestinal failure because they are unable to maintain fluid and nutrient balances on a normal diet. SBS can cause various metabolic and physiologic disturbances. Although parenteral nutrition is a life-saving measure for many patients with SBS, patients with SBS is associated with decreased survival and parenteral nutrition (PN) dependence. Few studies have reported the survival and PN dependence in adult SBS patients in China.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Retrospective

入排标准

年龄范围
18 Years 至 100 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Adult patients diagnosed with SBS.

排除标准

  • age <18 years; patients with active malignant tumors.

结局指标

主要结局

Survival

时间窗: 2012/1/1-2019/1/1

Survival rate in patients with SBS

Parenteral nutrition dependence

时间窗: 2012/1/1-2019/1/1

Parenteral nutrition dependence in patients with SBS

次要结局

  • Risk factors(2012/1/1-2019/1/1)
  • Cause of death(2012/1/1-2019/1/1)

研究者

发起方
The First Affiliated Hospital of University of Science and Technology of China
申办方类型
Other
责任方
Sponsor

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