Early Remote At-risk Diagnosis for Cerebral Palsy in Follow-up Clinics for High-risk Infants
- Conditions
- Cerebral Palsy
- Registration Number
- NCT04287166
- Lead Sponsor
- St. Olavs Hospital
- Brief Summary
Cerebral Palsy (CP) is the most common motor dysfunction in childhood. Traditionally, diagnosis is set between 12 and 24 months of age. This study will evaluate feasibility of a new screening procedure for early detection of CP in high-risk infants and investigate how such a procedure can be implemented in the Central Norwegian Regional Health Authority (CNRHA).
The most accurate method to detect and predict CP at an early age is the General Movement Assessment (GMA). GMA is based upon expert observations of infant spontaneous movements in a video. In Central-Norway such expertise is today only present at St. Olavs Hospital, Trondheim University Hospital. Video recordings by health personnel and parents will be used in follow-up programs within CNRHA for remote expert based GMA. In addition, machine learning models will be applied for automatic detection of CP.
Early identification of CP will lead to improved function and increased possibility to direct health care resources to the patients who need it most, independent of geographical and expert based constraints.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ACTIVE_NOT_RECRUITING
- Sex
- All
- Target Recruitment
- 100
- hospitalized at a Neonatal Intensive Care Unit (NICU) within the Central Norway Regional Health Authority that is referred to follow-up in the Specialist Health Services containing a team of minimum a pediatrician and a physiotherapist.
- at high-risk for adverse neurological outcomes as considered by the pediatrician on the basis of clinical judgement (example: serious asphyxia, prematurity, stroke, brain hemorrhage)
- Peripheral neuromotor disease e.g. brachial plexus injury
- iatrogenic restricted movements (e.g. cast for clubfoot)
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Predictability of GMA and computer-based assessment for development of CP 5 years Correlation of computer software data between standard video set-up and handheld smartphone video. 1 week Scorable video for remote GMA 1 week
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (3)
Department of Pediatrics, Nord-Trøndelag Hospital Trust
🇳🇴Levanger, Norway
Department of Pediatrics, St. Olav's Hospital Trust
🇳🇴Trondheim, Norway
Department of Pediatrics, Møre and Romsdal Hospital Trust
🇳🇴Ålesund, Norway