Immediate and Mid-term Implications of the Covid-19 Pandemic on the Physical, Behavioural and Mental Health of Healthcare Workers: A Cohort Study of Doctor, Nurses and Other Health Care Workers
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 1,721
- 试验地点
- 1
- 主要终点
- Change in proportion of who report a combined outcome of either presence of anxiety or depression from baseline to the end of study
研究概览
简要总结
The current COVID-19 pandemic has affected more than 3 million people worldwide across more than 200 countries.
In the United Kingdom alone, at the end of April, there were almost 160,000 confirmed cases with more than 20,000 deaths. This has undoubtedly had significant physical and economical impact on the public.
Healthcare workers are at high risk of developing life-threatening infectious diseases with increased exposure to patients' blood and bodily fluids. As such, health care workers arguably experience heightened anxiety and are predisposed to greater negative psycho-social impact from the current COVID-19 pandemic.
The aim of this study is to evaluate the physical and psychological impact of COVID-19 on healthcare workers. This will be performed in two phases.
In phase 1, investigators will collect information to evaluate the current psychiatric symptom profile (in particular, screening for anxiety or depression related symptoms), alcohol use, sleep-related complaints and overall well-being among healthcare workers who participate in this survey (with a focus on junior doctors). In addition the association of these mental health and behavioural parameters with the prevalence of stressful occasions, such as long-hours, unpredictability of work / redeployment, availability of personal protection equipment and concerns regarding family/relationship and self will be assessed.
In phase 2, investigators will then reassess for the development or progression of psychiatric symptoms, use of alcohol and other substances, behavioural or interpersonal relationship changes as well as physical well-being at 6 weeks and 4- months. Physical well-being is assessed through the presence of suspected or confirmed COVID-19 infection and absence from work. Specifically, investigators will study the impact of variable provision of personal protection equipment (supply and training), extended working hours, and concern for well-being of family members, on work morale and anxiety levels.
Another aim is also study the longer term mental health consequences of the current pandemic on health care workers.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Electronic consent
- •a - healthcare workers in contact with patients with confirmed or suspected COVID-19 b - Healthcare staff not having direct patient contact c - Non-healthcare academic staff with no direct patient contact
排除标准
- •Individuals not belonging to the 3 cohorts of interest listed in the inclusion criteria.
- •Those who are not able to understand written English will be excluded, indeed by the design and methodology of the study, as the study invite and all other information provided is in English.
结局指标
主要结局
Change in proportion of who report a combined outcome of either presence of anxiety or depression from baseline to the end of study
时间窗: 4 months
Anxiety will be investigated by 7-item Generalised Anxiety Disorder and depression will be investigated by 9-item patient health questionnaire. Presence of either one of those or both will be taken as the combined outcome. For anxiety, 7-item Generalized anxiety disorder score (GAD- 7) Scores of 5, 10, and 15 are taken as the cut-off points for mild, moderate and severe anxiety, respectively. Higher score corresponding to more severe degree of anxiety. For depression, the 9- item Patient Health Questionnaire (PHQ-9). Min score of severity: 0-4 none, 20-27 severe. Higher score corresponding to more severe degree of depression
Presence of anxiety at baseline
时间窗: baseline
Symptoms of anxiety will be investigated using the 7-item Generalised Anxiety Disorder (GAD- 7) Scores of 5, 10, and 15 are taken as the cut-off points for mild, moderate and severe anxiety, respectively. Higher score corresponding to more severe degree of anxiety.
Presence of depression at baseline
时间窗: baseline
Symptoms of depression will be investigated using the 9- item Patient Health Questionnaire (PHQ-9). Min score of severity: 0-4 none, 20-27 severe. Higher score corresponding to more severe degree of depression
Proportion of those who report a combined outcome of presence of anxiety or depression at the baseline as determined by screening questionnaires used.
时间窗: baseline
Anxiety will be investigated by 7-item Generalised Anxiety Disorder and depression will be investigated by 9-item patient health questionnaire. Presence of either one of those or both will be taken as the combined outcome. For anxiety, 7-item Generalized anxiety disorder score (GAD- 7) Scores of 5, 10, and 15 are taken as the cut-off points for mild, moderate and severe anxiety, respectively. Higher score corresponding to more severe degree of anxiety. For depression, the 9- item Patient Health Questionnaire (PHQ-9). Min score of severity: 0-4 none, 20-27 severe. Higher score corresponding to more severe degree of depression Higher score corresponding to more severe degree of anxiety.
Change in the proportion of those who report signs and symptoms or evidence consistent with probable diagnosis of COVID-19 from baseline to the end of study
时间窗: 4 months
Self reported, assessed based on the questions regarding the presence of symptoms with presence of either self reported positive test, or self-isolation of 7 or more days.
次要结局
- Change in prevalence of sleep-related issues from baseline(4-month follow-up)
- Change in proportion of those with low mental wellbeing from baseline to the end of study.(4-month follow-up)
- Prevalence of sleep-related issues at baseline(At baseline)
- Change in behavioural habits, such as smoking and alcohol intake from baseline to the end of study(4-month follow-up)
- Prevalence of a combined outcome of presence of anyone of anxiety, depression or sleep related issues at baseline.(baseline)
- Proportion of those with low mental wellbeing at baseline(baseline)
- Prevalence of those who report concern related to work-place practices.(At baseline)
- Change in prevalence of depression from baseline(4 months followup)
- Change in the prevalence from baseline of those who report concern related to work-place practices.(4 months)
- Change in prevalence of anxiety from baseline(4 months)
- Proportion of those who report signs and symptoms or evidence consistent with probable diagnosis of COVID-19(Baseline)