Ultrasound-guided Block for Thoracic Surgery Pain

Not Applicable

Completed

• Conditions: Thoracic Cancer; Postoperative Pain
• Interventions: Drug: patient controlled analgesia; Procedure: serratus anterior plane block

• Registration Number: NCT03240562
• Lead Sponsor: Samsung Medical Center

Brief Summary

The investigators aimed to assess Ultrasounde- guided serratus anterior plane block can be effective in acute postoperative pain following thoracic surgery.

Detailed Description

Analgesic options for thoracotomy are various with each having their own merits and demerits.Thoracic epidural is said to be the gold standard for management of thoracotomy pain. However, it is invasive procedure and many side effects. Other options include paravertebral block, interpleural block, intrathecal opioids. Especially, paravertebral block is thought good alternative to epidural anethesia. Most of these invasive neuraxial techniques demand normal coagulation parameters to be present.

The serratus anterior plane block(SAPB) was done under ultrasound guidance in the mid-axillary line at the level of the fourth rib and the catheter was placed superficial to the serratus plane. The patient expressed relief in pain within 10 minutes of being given the bolus of local anaesthetic.Pain following thoracotomy is chiefly due to rib retraction, and damage to the serratus/intercostal muscles and intercostal nerves. A SAPB addresses both these aspects. SAPB has been mentioned in previous studies for management of rib fractures and breast surgeries. The investigators try to evaluate whether the SAPB is easy to perform and provides effective analgesia in patients undergoing thoracotomy with minimal side effects.

Basic Information
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Recruitment & Eligibility
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Study & Design
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Trial Locations

Study Timeline

• Status Verified: 2017-07
• Study First Submitted: 2017-07-28
• Study First Submitted QC: 2017-08-01
• Study Start: 2017-08-03
• Study First Posted: 2017-08-07
• Primary Completion: 2017-11-30
• Study Completion: 2017-12-30
• Last Update Submitted: 2018-02-26
• Last Update Posted: 2018-02-28

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 89

Inclusion Criteria

•undergoing thoracic surgery (lobectomy or segmentectomy)

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Exclusion Criteria

• allergy to any drugs chronic pain disease with medication psychologic disorder anti-depressant drug chronic kidney disease ( Cr over 2.0 mg/dl) coagulopathy

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Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
IV-PCA group	patient controlled analgesia	no block performing, only use intravenous patient controled analgesia(IV-PCA)
SAPB group	serratus anterior plane block	serratus anterior plane block(SAPB) and intravenous patient controled analgesia(IV-PCA)
SAPB group	patient controlled analgesia	serratus anterior plane block(SAPB) and intravenous patient controled analgesia(IV-PCA)

Primary Outcome Measures

Name	Time	Method
opioid consumption	the first 24hour in postoperative phase	the dose of PCA and residual opioid

Secondary Outcome Measures

Name	Time	Method
postoperative pain scale	intraoperative(immediately after surgery), postoperative 6 ,12, 24 hour	numeric rating scale
opioid consumption	the first 6,12 hour in postoperative phase	the dose of PCA and residual opioid

Trial Locations

Locations (1)

Samsung medical center; 🇰🇷 Seoul, Korea, Republic of