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Evaluation of Exercise Application Technology in Adolescents

Not Applicable
Withdrawn
Conditions
Type 2 Diabetes
PreDiabetes
Obesity
Interventions
Device: continuous glucose monitor (Freestyle Libre
Registration Number
NCT05720377
Lead Sponsor
University of Alabama at Birmingham
Brief Summary

The purpose of the study is to evaluate the use of an exercise phone application and a continuous glucose monitor and their impact on metabolic disease in adolescents with obesity, prediabetes and Type 2 diabetes. Participants will be asked to wear a continuous glucose monitor (Freestyle Libre) and if they are in the intervention group also participate in using an exercise phone application as well as have scheduled interval contact with a health professional in between scheduled clinic visits to assess how they are reaching their goals.

Detailed Description

Patients will be recruited directly from the Childrens of Alabama pediatric endocrine clinic. Thirty patients who have obesity, prediabetes or Type 2 diabetes will be enrolled. During the enrollment phase, flyers will be posted in clinic and emails will be distributed to potential participants. Our study team will approach interested participants during their routine clinic visit. Consent will be obtained by study team during their endocrine clinic visit. Review of their medical records will be done and age, gender and race will be extracted from the medical record. A baseline visit with vital signs, blood work, a physical exam and nutritional counseling will be completed. Once enrolled, the patients will then be randomized.Within this pilot trial, we will randomize 15 adolescents/teenagers who either have obesity, prediabetes or Type 2 diabetes, to access to an exercise regimen and 15 adolescents to control intervention using a permuted block randomization scheme. The randomization scheme will contain 6 blocks of size 5 allowing for 30 randomized in the group with obesity, prediabetes and Type 2 diabetes.

Those who are in the intervention group will then be given access to frequent telephone counseling to follow-up their nutrition and exercise goals, access to exercise application and accelerometer as described below. Follow-up will then be completed at 3 and 6 months with a physical exam, vital signs, blood draw.

Intervention Group

Access provided to exercise application Provided with Fitbit to wear and measure activity Weekly check-in with provider to determine how exercise goals have been that week. If unable to reach, we will text securely a clinic check-in and provide a healthy tip of the week.

Meeting with nutrition at Baseline visit

Continuous glucose monitor provided (plan to wear for 14 days during each month)

Non-Intervention Group

Meeting with nutrition at Baseline visit

Continuous glucose monitor provided (plan to wear for 14 days at baseline visit, 3 month visit and 6 month visit)

Recruitment & Eligibility

Status
WITHDRAWN
Sex
All
Target Recruitment
Not specified
Inclusion Criteria

Not provided

Exclusion Criteria

Not provided

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
Prediabetes, receives access to exercise phone applicationcontinuous glucose monitor (Freestyle Libreprediabetes receives access to exercise phone application and interval contact by health provider in between clinic visit, receives continuous glucose monitor
Obese, receives access to exercise phone applicationcontinuous glucose monitor (Freestyle Libreobese, receives access to exercise phone application and interval contact by health provider in between clinic visits , receives continuous glucose monitor
Type 2 diabetes, receives access to exercise phone applicationcontinuous glucose monitor (Freestyle Libreprediabetes receives access to exercise phone application and interval contact by health provider in between clinic visit, receives continuous glucose monitor
Primary Outcome Measures
NameTimeMethod
skin fold thicknessbaseline

reliable estimate of subcutaneous fat at various sites of the body

skin fold measurement6 month

reliable estimate of subcutaneous fat at various sites of the body

Body mass index3 month

measure of body fat based on height and weight

Body Mass Index6 month

measure of body fat based on height and weight

Secondary Outcome Measures
NameTimeMethod
IL-66 months

inflammatory marker in the blood

TNF-alpha6 months

inflammatory marker in the blood

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