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Risk Factors and Deep Learning Model for CI-AKI

Active, not recruiting
Conditions
AKI - Acute Kidney Injury
Registration Number
NCT06596785
Lead Sponsor
Xiao Li,MD
Brief Summary

Contrast-associated acute kidney injury (CI-AKI) is a sudden and significant decline in renal function resulting from the use of a contrast agent.

Detailed Description

Contrast-associated acute kidney injury (CI-AKI) is a sudden and significant decline in renal function resulting from the use of a contrast agent. Despite the frequent use of iodinated contrast agents in medical investigations, predictive models for CI-AKI are scarce. This study aimed to construct and validate interpretable deep learning models for the early risk prediction of acute kidney injury (AKI) associated with iodinated contrast agents.

Recruitment & Eligibility

Status
ACTIVE_NOT_RECRUITING
Sex
All
Target Recruitment
2000
Inclusion Criteria
  • patients who received iodinated contrast agents during hospitalization
  • age ≥ 18 years
  • hospitalization length ≥ 48 hours
  • at least two serum creatinine tests during hospitalization
Exclusion Criteria
  • patients with stage 4 or 5 chronic kidney disease prior to admission
  • patients undergoing hemodialysis, hemofiltration or peritoneal before admission
  • a history of nephrectomy or kidney transplantation during hospitalization
  • incomplete clinical information
  • Serum creatinine always ≤ 40 μmol/L during hospitalization

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
AKICompleted through study, up to half a year

During the patient's hospitalization, acute kidney injury occurred after the use of Iodinated contrast media

Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (1)

The First Affiliated Hospital of Shandong First Medical University & Shandong Provincial Qianfoshan Hospital

🇨🇳

Jinan, Shandong, China

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