Awake Prone Position in Critical and Severe COVID-19 Patients Undergoing Noninvasive Respiratory Support: a Retrospective Multicenter Cohort Study

University of Modena and Reggio Emilia1 site in 1 country93 target enrollmentMarch 1, 2020

ConditionsCovid19

Overview

Phase: Not Applicable
Intervention: Not specified
Conditions: Covid19
Sponsor: University of Modena and Reggio Emilia
Enrollment: 93
Locations: 1
Primary Endpoint: Endotracheal intubation
Status: Completed
Last Updated: 5 years ago

Overview Investigators Eligibility Criteria Outcomes Sites Similar Trials

Overview

Brief Summary

Pronation seems feasible and effective in improving blood oxygenation in patients with COVID-19 pneumonia. Data are lacking on the effects of pronation on clinical outcome in this subset of patients.

Registry

clinicaltrials.gov

Start Date

March 1, 2020

End Date

November 30, 2020

Last Updated

5 years ago

Study Type

Observational

Sex

All

Investigators

Sponsor

University of Modena and Reggio Emilia

Responsible Party

Principal Investigator

Roberto Tonelli

University of Modena and Reggio Emilia

Eligibility Criteria

Inclusion Criteria

•Inclusion Criteria
•patients aged ≥18 and \< 80 years old
•acute respiratory failure

Exclusion Criteria

•endotracheal intubation performed within the first 24 hours from admission,
•ceiling of escalation of intensive care
•do not intubate order as expressed by patient willing or upon clinical judgement
•missing core data at medical record analysis (clinical features at baseline, pronation information, type and time of ventilatory support required, mortality, need for tracheostomy, length of respiratory intensive care unit and hospital stay).