A RCT on Supraglottic Airway Versus Endotracheal Intubation in OHCA (SAVE)
试验速览
- 阶段
- 不适用
- 入组人数
- 852
- 主要终点
- survival to admission
研究概览
简要总结
In this 3-year successive research plan, investigators will conduct a prehospital randomized controlled trial to address the following question: In adult patients with non-traumatic cause of out-of-hospital cardiac arrest resuscitated by emergency medical technician (paramedic level) in the prehospital setting, will receiving endotracheal tube intubation cause a better chance of sustained recovery of spontaneous circulation and other survival outcomes like neurologically favorable status, comparing to those who receiving supraglottic airway device.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Double (Participant, Outcomes Assessor)
入排标准
- 年龄范围
- 20 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •out-of-hospital cardiac arrest; OHCA
- •age ≥ 20 years old
- •non-traumatic cause
排除标准
- •signs of obvious death, eg. decapitation or rigor mortis
- •theoretically not suitable for ETI, eg. facial deformity or third-trimester pregnancy
- •theoretically not suitable for SGA, eg. foreign-body airway obstruction
- •with "do not attempt resuscitation" order
- •the occurrence of OHCA during ambulance transport
- •ROSC in the field with clear consciousness and spontaneous adequate ventilation
- •advanced airway being established before the arrival of paramedics
研究组 & 干预措施
supraglottic airway (SGA)
Adult patients with non-trauma causes of OHCA who are resuscitated by emergency medical technician paramedic (EMTP) in the prehospital setting and received airway management of supraglottic airway (SGA).
干预措施: supraglottic airway (SGA) V.S. endotracheal intubation (ETI) (Device)
endotracheal intubation (ETI)
Adult patients with non-trauma causes of OHCA who are resuscitated by emergency medical technician paramedic (EMTP) in the prehospital setting and received airway management of endotracheal intubation (ETI).
干预措施: supraglottic airway (SGA) V.S. endotracheal intubation (ETI) (Device)
结局指标
主要结局
survival to admission
时间窗: One month after event
Measurement of outcome by standard Utstein OHCA registry system in Taipei City
次要结局
- survival to discharge(One month after event)
- favorable neurologic outcome(One month after event)
- any ROSC(One month after event)