Impact of Non-surgical Periodontal Treatment of miRNome
- Conditions
- Periodontitis
- Interventions
- Other: Probin Pocket Depth reduction
- Registration Number
- NCT06382935
- Lead Sponsor
- University of Catania
- Brief Summary
A double-blind randomized-controlled clinical trial is conducted in order to evaluate the impact of non-surgical periodontal treatment by means of minimally invasive approach MINST or Q-SI (quadrantwise) approach in subjects with periodontitis on miRNome in gingival crevicular fluid
- Detailed Description
A double-blind randomized-controlled clinical trial is conducted in order to evaluate the impact of non-surgical periodontal treatment in subjects with periodontitis.
60 patients: 30 with periodontitis and 30 healthy controls. All the patients are assessed for clinical, periodontal, blood following of minimally invasive approach MINST or Q-SI (quadrantwise).
Measurements are taken before and after initial periodontal treatment in the periodontal subjects.
Recruitment & Eligibility
- Status
- RECRUITING
- Sex
- All
- Target Recruitment
- 60
- Diagnosis of Periodontitis
- Periodontal treatment
- Use of antibiotics, NSAIDs, and immunosuppressants during the last 6 months
- Pregnancy
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description Q-SI non surgical periodontal treatment Probin Pocket Depth reduction Periodontitis patients treated by means of Q-SI. Patients were treated with non-surgical quadrantwise periodontal treatment in 4 sessions, 1 session per week. MINST non surgical periodontal treatment Probin Pocket Depth reduction Periodontitis patients treated by means of MINST. Patients were treated with non-surgical MINST periodontal treatment in a single session.
- Primary Outcome Measures
Name Time Method Probing Pocket Depth 6-months Reduction in Probing Pocket Depth after treatnebt
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
AOU Policlinico G. Rodolico
🇮🇹Catania, Italy