Impact of Non-surgical Periodontal Treatment of miRNome

Not Applicable

Recruiting

• Conditions: Periodontitis

• Registration Number: NCT06382935
• Lead Sponsor: University of Catania

Brief Summary

A double-blind randomized-controlled clinical trial is conducted in order to evaluate the impact of non-surgical periodontal treatment by means of minimally invasive approach MINST or Q-SI (quadrantwise) approach in subjects with periodontitis on miRNome in gingival crevicular fluid

Detailed Description

A double-blind randomized-controlled clinical trial is conducted in order to evaluate the impact of non-surgical periodontal treatment in subjects with periodontitis.

60 patients: 30 with periodontitis and 30 healthy controls. All the patients are assessed for clinical, periodontal, blood following of minimally invasive approach MINST or Q-SI (quadrantwise).

Measurements are taken before and after initial periodontal treatment in the periodontal subjects.

Study Timeline

• Status Verified: 2024-04
• Study Start: 2024-04-20
• Study First Submitted: 2024-04-20
• Study First Submitted QC: 2024-04-20
• Last Update Submitted: 2024-04-20
• Study First Posted: 2024-04-24
• Last Update Posted: 2024-04-24
• Primary Completion: 2024-09-22
• Study Completion: 2024-10-15

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

• Diagnosis of Periodontitis

Exclusion Criteria

• Periodontal treatment
• Use of antibiotics, NSAIDs, and immunosuppressants during the last 6 months
• Pregnancy

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
Probing Pocket Depth	6-months	Reduction in Probing Pocket Depth after treatnebt

Trial Locations

Locations (1)

AOU Policlinico G. Rodolico; 🇮🇹 Catania, Italy