Thoracic Mobilization for Restrictive Lung Disease

Not Applicable

Not yet recruiting

• Conditions: Restrictive Lung Disease

• Registration Number: NCT07012733
• Lead Sponsor: Chungnam National University Sejong Hospital

Brief Summary

This study aims to investigate the immediate effects of thoracic mobilization techniques on cough capacity, dyspnea, and pulmonary function in patients with restrictive lung disease. The intervention will be applied in a single session, and outcomes will be measured before and after the intervention to evaluate short-term physiological changes.

Detailed Description

Restrictive lung disease (RLD) is characterized by reduced lung compliance and limited thoracic mobility, leading to decreased lung volume and impaired respiratory function. Manual therapy interventions such as thoracic mobilization have been proposed to improve chest wall flexibility and enhance respiratory efficiency. However, few studies have examined the immediate clinical effects of such interventions in RLD patients.

This single-group pre-post interventional study will evaluate the short-term outcomes of thoracic mobilization techniques on cough capacity (as measured by peak cough flow), dyspnea (via Borg scale), and pulmonary function (forced vital capacity \[FVC\], forced expiratory volume in 1 second \[FEV1\]). The results are expected to provide preliminary evidence on the effectiveness of thoracic mobilization for improving respiratory performance in individuals with RLD.

Study Timeline

• Study First Submitted: 2025-05-22
• Status Verified: 2025-06
• Study First Submitted QC: 2025-06-01
• Last Update Submitted: 2025-06-01
• Study Start: 2025-06-09
• Study First Posted: 2025-06-10
• Last Update Posted: 2025-06-10
• Primary Completion: 2025-11-18
• Study Completion: 2025-12-26

Recruitment & Eligibility

• Status: NOT_YET_RECRUITING
• Sex: All
• Target Recruitment: 24

Inclusion Criteria

• Age 19 years or older
• Currently receiving respiratory therapy at C Hospital in Sejong City
• Pulmonary function test indicating restrictive pattern: FVC < 80% and FEV1/FVC ≥ 70%
• FVC above the lower limit of normal (LLN) for age and sex
• Diagnosed with restrictive lung disease, such as idiopathic pulmonary fibrosis, scoliosis, or neuromuscular disorders (e.g., myopathy, amyotrophic lateral sclerosis)

Exclusion Criteria

• FEV1/FVC ratio < 70%
• Evidence of airway obstruction on pulmonary function testing

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
Pulmonary function test	Immediately before and immediately after intervention on Day 1	Pulmonary function will be assessed using a standard spirometry test, including FVC and FEV1. The test will be conducted by a trained technician according to ATS/ERS guidelines to evaluate respiratory function.

Secondary Outcome Measures

Name	Time	Method
Cough peak flow	Immediately before and immediately after intervention on Day 1	Cough peak flow will be measured using a peak flow meter. Participants will be instructed to perform a maximal voluntary cough following a deep inspiration, and the highest value from three trials will be recorded. The assessment will be conducted by a trained therapist to evaluate cough capacity.
Dyspnea	Immediately before and immediately after intervention on Day 1	Dyspnea will be assessed using the modified Borg scale, a subjective rating scale ranging from 0 (no breathlessness) to 10 (maximum breathlessness). Participants will rate their perceived level of dyspnea at rest following the intervention. The assessment will be administered by a trained therapist.

Trial Locations

Locations (1)

Chungnam National University Sejong Hospital; 🇰🇷 Sejong, Korea, Republic of