Does the Incremental Shuttle Walk Test Predict the Development of a Hospital Acquired Pneumonia in Patients Undergoing Elective Oesophagectomy: A Prospective Cohort Study

Completed

• Conditions: Oesophageal Cancer

• Registration Number: NCT04440124
• Lead Sponsor: University Hospital Birmingham NHS Foundation Trust

Brief Summary

The purpose of this study was to assess the predictive value of the incremental shuttle walk test on rates of hospital acquired pneumonia for patients undergoing oesophagectomy.

Detailed Description

Field tests to objectively measure functional capacity are becoming of greater importance when looking to assess an individual's fitness for surgery. One such field test is the incremental shuttle walk test (ISWT). An externally paced, maximal excursion test, the ISWT is a simple and easily reproducible test that is widely used within cardiac and pulmonary populations and shown to correlate well with Vo2 mas on a cardiopulmonary exercise test. Previous studies looking at the benefit of the ISWT in predicting post-operative outcomes within the oesophagastric population have demonstrated that walking less than 350 meters has been associated with significantly higher rates of mortality at 30 days and 3 years. No correlation between ISWT and postoperative respiratory complications in this surgical population has been previously reported.

This study aims to assess whether walking \<350 meters on an ISWT predicts the development of hospital acquired pneumonias following an elective oesophagectomy

Study Timeline

• Study Start: 2017-12-01
• Primary Completion: 2020-02-01
• Study Completion: 2020-02-01
• Status Verified: 2020-06
• Study First Submitted: 2020-06-14
• Study First Submitted QC: 2020-06-17
• Last Update Submitted: 2020-06-17
• Study First Posted: 2020-06-19
• Last Update Posted: 2020-06-19

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 121

Inclusion Criteria

• Consecutive patients with a diagnosis of oesophagogastric cancer listed for an elective oesophagectomy at a large UK tertiary hospital

Exclusion Criteria

• Patients who were unable to complete the walking test
• patients deemed not fit for surgery
• patients with a significant neurological event peri or post operatively

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Hospital acquired pneumonia	during hospital stay, on average 14 days	The incidence of hospital acquired pneumonia as defined by the US centres for Disease Control

Secondary Outcome Measures

Name	Time	Method
90 day Mortality	90 days following date of surgery	Mortality rates 90 days post operatively
30 day Mortality	30 days after date of surgery	Mortality rates 30 days post operatively

Trial Locations

Locations (1)

UHB NHS Foundation Trust; 🇬🇧 Birmingham, United Kingdom