Heterogeneity and Development of Early COPD
Recruiting
- Conditions
- Chronic Obstructive Pulmonary Disease
- Registration Number
- NCT06096285
- Lead Sponsor
- China-Japan Friendship Hospital
- Brief Summary
This study aims to investigate the clinical characteristics and heterogeneities of early chronic obstructive pulmonary disease (COPD), to determine the disease development of early COPD, and to establish a multidimensional model for predicting the outcomes of early COPD.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- RECRUITING
- Sex
- All
- Target Recruitment
- 84
Inclusion Criteria
- The individuals who meet the defining criteria of PRISm, COPD Stage 0, Pre-COPD, Early COPD, Young COPD, and Mild COPD, according to the latest GOLD documents and publications.
Exclusion Criteria
- Age < 18 years or > 80 years;
- Pregnant or maternal women;
- Having malignant and active tumor(s), and receiving treatment;
- Undergoing a surgical operation;
- Having problems with mental awareness;
- Having difficulties in daily activities;
- Participating in other interventional clinical trials.
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Number of participants with COPD exacerbation One year COPD exacerbation refers to acute deterioration of respiratory symptoms (e.g. cough, sputum, wheeze, dyspnea), especially resulting in hospital visit or admission.
- Secondary Outcome Measures
Name Time Method FVC% predicted value One year FVC One year FEV1 One year FEV1% predicted value One year The COPD Assessment Test scale One year The COPD Assessment Test scores range from 0 to 40, with higher scores indicating worse symptoms.
FEV1/FVC ratio One year The modified Medical Research Council dyspnea scale One year The modified Medical Research Council dyspnea scores range from 0 to 4, with higher scores indicating more severe dyspnea.
Trial Locations
- Locations (1)
China-Japan Friendship Hospital
🇨🇳Beijing, Beijing, China