跳至主要内容
临床试验/ISRCTN29594895
ISRCTN29594895进行中(未招募)未知

A randomised feasibility study evaluating the effect of perioperative intravenous lIdocaine on colorectal cancer outcome after surgery

Chelsea and Westminster Hospital0 个研究点目标入组 50 人开始时间: 2022年4月6日最近更新:
适应症

试验速览

阶段
未知
状态
进行中(未招募)
发起方
入组人数
50

研究概览

简要总结

2023 Protocol article in https://pubmed.ncbi.nlm.nih.gov/37387798/ (added 03/07/2023)

研究设计

研究类型
Interventional

入排标准

性别
All

入选标准

  • 1. Aged 18 years and above, undergoing laparoscopic surgery with stage 2 or 3 colon cancer
  • 2. Ability and willingness to consent

排除标准

  • 1. Stage 1 and stage 4 colon or rectal cancer
  • 2. Palliative surgery with no curative intent
  • 3. Extensive comorbidities, i.e. American Society of Anesthesiologists (ASA) Score IV
  • 4. Patients with known allergy to lidocaine
  • 5. Patients who are pregnant or breastfeeding
  • 6. Patients who are likely to have adverse effects from the accumulation of intravenous lidocaine:
  • 6.1. Known liver disease with liver function outside the normal laboratory range
  • 6.2. Epilepsy
  • 6.3. Cardiac conduction abnormalities based on history and confirmed by electrocardiogram

研究者

发起方
Chelsea and Westminster Hospital

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