Feasibility study of lidocaine infusion during bowel cancer surgery for cancer outcome

Not Applicable

• Conditions: Cancer; Colorectal cancer patient undergoing surgery for cancer resection

• Registration Number: ISRCTN29594895
• Lead Sponsor: Chelsea and Westminster Hospital

Brief Summary

2023 Protocol article in https://pubmed.ncbi.nlm.nih.gov/37387798/ (added 03/07/2023)

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2022-04-06
• Last Update Posted: 3 October 2023
• Study Completion: 2024-09-15

Recruitment & Eligibility

• Status: Ongoing
• Sex: All
• Target Recruitment: 50

Inclusion Criteria

1. Aged 18 years and above, undergoing laparoscopic surgery with stage 2 or 3 colon cancer
2. Ability and willingness to consent

Exclusion Criteria

1. Stage 1 and stage 4 colon or rectal cancer
2. Palliative surgery with no curative intent
3. Extensive comorbidities, i.e. American Society of Anesthesiologists (ASA) Score IV
4. Patients with known allergy to lidocaine
5. Patients who are pregnant or breastfeeding
6. Patients who are likely to have adverse effects from the accumulation of intravenous lidocaine:
6.1. Known liver disease with liver function outside the normal laboratory range
6.2. Epilepsy
6.3. Cardiac conduction abnormalities based on history and confirmed by electrocardiogram

Study & Design

• Study Type: Interventional
• Study Design: Not specified