Medical Access Program for Patritumab Deruxtecan
- Conditions
- Epidermal Growth Factor Receptor (EGFR)-Mutated Non Small Cell Lung Cancer
- Registration Number
- NCT06099639
- Lead Sponsor
- Daiichi Sankyo
- Brief Summary
The purpose of this Medical Access Program is to provide access to HER3-DXd for eligible patients with NSCLC who, in their treating physician's opinion, have an unmet clinical need which cannot be treated with approved and commercially available drugs and who cannot enter a clinical trial prior to commercial availability.
- Detailed Description
This is a Medical Access Program which will be available to adult patients in the US with metastatic or locally advanced EGFRm NSCLC who have received at least 2 prior systemic therapies, who have no alternative commercially available treatment options, and are not able to enter a clinical trial.
In this Medical Access Program, eligible patients will be treated with HER3-DXd and will continue to receive treatment until any of the following occurs:
* Disease progression
* Unacceptable toxicity
* The benefit-risk no longer favors the individual
* HER3-DXd becomes commercially available in the US and reimbursement is approved for the concerned indication of the Medical Access Program.
* Withdrawal of consent
* Pregnancy
* Physician discretion
* Death
Recruitment & Eligibility
- Status
- AVAILABLE
- Sex
- All
- Target Recruitment
- Not specified
Not provided
Not provided
Study & Design
- Study Type
- EXPANDED_ACCESS
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (21)
The Washington University
🇺🇸Saint Louis, Missouri, United States
Highlands Oncology
🇺🇸Springdale, Arkansas, United States
Southern California Permanente Medical Group
🇺🇸Los Angeles, California, United States
University of Colorado
🇺🇸Aurora, Colorado, United States
Yale-New Haven Hospital
🇺🇸New Haven, Connecticut, United States
Advent Health
🇺🇸Orlando, Florida, United States
University of Chicago Medical Center
🇺🇸Chicago, Illinois, United States
Block Medical Center
🇺🇸Skokie, Illinois, United States
Baptist Health Lexington
🇺🇸Lexington, Kentucky, United States
Karmanos Cancer Institute (Barbara Ann Karmanos Cancer Hospital)
🇺🇸Detroit, Michigan, United States
Mayo Clinic
🇺🇸Rochester, Minnesota, United States
Overlook Medical Center
🇺🇸Summit, New Jersey, United States
Roswell Park Comprehensive Cancer Center
🇺🇸Buffalo, New York, United States
Kettering Health Cancer Center
🇺🇸New York, New York, United States
The Mount Sinai Hospital- (Icahn School of Medicine)
🇺🇸New York, New York, United States
Messino Cancer Center
🇺🇸Asheville, North Carolina, United States
Duke Cancer Institute
🇺🇸Durham, North Carolina, United States
Providence Portland Medical Center
🇺🇸Portland, Oregon, United States
The Kaiser Permanente Medical Group
🇺🇸Portland, Oregon, United States
Texas Oncology
🇺🇸Pearland, Texas, United States
Peace Health
🇺🇸Bellingham, Washington, United States