NL-OMON54427尚未招募不适用
An exploratory pharmacokinetics and pharmacodynamics study of beta-lactam antibiotics in pediatric intensive care patients: is there a need for more precision? (EXPAT-Kids) - EXPAT-Kids
适应症
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 145
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 0 至 17（—）
入选标准
- •All patients admitted to the pediatric intensive care unit wards and given
- •standard of care intravenous therapy of target antibiotic are screened for
- •participating trial.
- •Antibiotic initiation based on clinical suspicion of infection and/or cultured
- •pathogens susceptible to the target drugs, initial dosage prescription, and
- •duration of therapy are at the discretion of the attending physician. In order
- •to be eligible to participate in this study a subject must also meet all the
- •followinng criteria:
- •Written informed consent has been obtained from the patient or their legally
- •authorized representative.
- •Recruitment within 36 hours after start of antibiotic therapy
- •Intravenous antibiotic therapy of the target antibiotic should be aimed for
- •at least 2 days.
排除标准
- •A potential subject who meets any of the following criteria will be excluded
- •from participation in this study:
- •Premature infants
- •History of anaphylaxis for the study antibiotics
- •Consent not obtained
- •Study antibiotic cessation before blood collection
- •Prophylactic use of the study antibiotics
研究者
相似试验
尚未招募
不适用
An exploratory pharmacokinetics and pharmacodynamics study beta-lactam antibiotics in pediatric intensive care patients: is there a need for more precision?NL-OMON29496MRace150
已完成
不适用
The exploration for pharmacodynamics and pharmacokinetic interaction between YH4808, amoxicillin and clarithromycin in healthy subjectsDiseases of the digestive systemKCT0000888Yuhan32
招募中
不适用
An exploratory pharmacokinetic and pharmacodynamic study of beta-lactam and fluoroquinolone in ICU patients10004018bacterial infectionSepsisNL-OMON43959Erasmus MC, Universitair Medisch Centrum Rotterdam200
进行中（未招募）
1 期
study of the pharmacokinetics and pharmacodynamics of desmopressin oral lyophilisate - route of administration in the pediatric patient population - SAFEPEDRUGEUCTR2014-005200-13-BEGhent University24
已完成
2 期
The acceptability, safety and tolerability of combined methadone-naloxone in methadone maintained individuals aged between 18 - 65ACTRN12608000024347angton Centre10