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Evaluation of the efficacy of the formulation of topical anesthesia of Lidocaine / Articaine 4% and Lidocaine / Prilocaine 2.5% with and without Sodium Bicarbonate in the mucosa located posterior to upper canine teeth

Phase 1
Conditions
Anxiety Disorders
F06.4
Registration Number
RBR-36y2xg
Lead Sponsor
niversidade Federal de Sergipe
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
ot yet recruiting
Sex
Not specified
Target Recruitment
Not specified
Inclusion Criteria

Criteria for inclusion of volunteers in the research: age between 18-35 years; ability to provide written consent; Undergraduate or graduate student of the dentistry department of the Federal University of Sergipe who has already undergone local anesthesia without intercurrences; Not having undergone anesthesia in the region in the two weeks prior to the study; Do not use medication that changes perception of pain in the 2 weeks prior to the study; Do not present systemic changes or a history of hypersensitivity to the drugs under study.

Exclusion Criteria

Individuals will be informed that it is permissible to leave the study at any time without any loss. The individual may be withdrawn from the study when he or she experiences an allergic reaction or clearly drug-related allergic reaction; To present non-drug-related systemic disease during the study, requiring concomitant therapy; Failure to comply with protocol requirements, including rules related to drug use, alcohol or lack of cooperation during the study.

Study & Design

Study Type
Intervention
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
All four groups of topical anesthetics present a latency time of fewer than 10 minutes and a duration of at least 10 minutes, verified through the dispositive, which contains calibrated filaments, mounted on supports and protected inside transparent tubes. The filaments are calibrated to undergo flexion with predetermined force.<br>;We also hope that the four topical anesthetics present efficiency in the control of pain during local anesthesia, verified through the visual analog scale, The Visual Analog Scale (EAV) is a 10cm line with no numbers or demarcations except at the ends where there are 0 (zero) and 10 (ten) markings. Marking 0 corresponds to no pain, and marking 10 is the worst possible pain. The classification of the pain is made by placing a vertical mark on the line; the distance between the mark and the extremities 0 and 10 is measured by a millimeter ruler, evaluating the painful sensitivity of the volunteer (Jensen, Karoly, and Braver, 1986).
Secondary Outcome Measures
NameTimeMethod
Secondary outcomes are not expected
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