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Erector Spinae Plan Block for Postoperative Analgesia

Not Applicable
Completed
Conditions
Postoperative Pain
Interventions
Procedure: Erector Spinae Plan Block
Procedure: Oblique subcostal TAP
Registration Number
NCT03398564
Lead Sponsor
Al Jedaani Hospital
Brief Summary

Laparoscopic cholecystectomy is a widely employed procedure in ambulatory surgery. Pain after laparoscopic cholecystectomy arises significantly from port site incisions in the anterior abdominal wall. Innervation of the anterior abdominal wall is segmentally supplied by pain afferents in the plane of fascia between transversus abdominis and the internal oblique muscles. Opioids analgesia is used to control postoperative pain, but it carries the risk of increased nausea and vomiting, ileus and sedation that may delay hospital discharge.

Several techniques have been tried as.neuroaxial narcotics, intraperitoneal lavage of local anesthetic and transversus abdominis plan (TAP) block and successfully reduced opioid use and improve postoperative analgesia.

The ultrasound-guided erector spinae plan(ESP) block is a recently described technique which produces reliable unilateral analgesia at thoraco-lumbar dermatomes. ESP block carries the advantages of being simple, safe, easily recognizable by ultrasound, and a catheter can be threaded to extend the duration of analgesia.

Few case series reported the efficacy of (US)-guided ESP blocks in reducing postoperative pain and opioids consumption.

Because of that, the investigators aimed to test the hypothesis that US-guided ESP blocks can decrease opioid consumption during the first 24 h after of laparoscopic cholecystectomy in comparison with the conventional systemic analgesia.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
70
Inclusion Criteria
  • 60 ASA I- II adult patients
  • 20-60 years old
  • elective laparoscopic cholecystectomy
  • Body mass index (BMI) less than 35
  • Port sites at or above thoracic T 10 dermatome
Exclusion Criteria
  • Allergy to amino-amide local anesthetics
  • Presence of coagulopathy
  • Local skin infection at the needle puncture sites
  • Preoperative chronic dependence upon opioid and NSAID medications
  • Liver or renal insufficiency
  • History of psychiatric or neurological disease
  • Deafness
  • previous open surgery that need the conversion of laparoscopic to open surgery or manipulations more than expected with more tissue trauma
  • American Society of Anesthesiologists (ASA) above Class II

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
Group I (Control)Erector Spinae Plan Blockultrasound guided Bilateral Erector Spinae Plan Block using isotonic saline
Group II (ESP)Erector Spinae Plan Blockultrasound guided Bilateral Erector Spinae Plan Block with bupivacaine 0.25%
Group III(OSTAP)Oblique subcostal TAPUltrasound-guided bilateral oblique subcostal TAP block
Primary Outcome Measures
NameTimeMethod
Morphine consumption24 hours postoperatively.

It was calculated as equivalent morphine dose to the opioid analgesia consumed

Secondary Outcome Measures
NameTimeMethod
Quality of analgesiaEvery 2 hours for 24 hours postoperatively

comparing visual analog scores (VAS) every two hours after surgery

Erector spinae plan block complications24 hours postoperative

local anesthetic systemic toxicity, vascular injury, and intravascular injection of local anesthetic

The intraoperative fentanyl2 hours

(µg) required during surgery

equivalent morphine dose in the recovery unit (PACU)one hour

equivalent morphine dose in the recovery unit (PACU)

Trial Locations

Locations (1)

Al Jedaani group of hospitals

🇸🇦

Jeddah, Meccah, Saudi Arabia

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