the Influence of General Anesthesia on Tumor Metastasis and Recurrence
- Conditions
- Tumor Recurrence and Metastasis
- Registration Number
- NCT02474511
- Lead Sponsor
- RenJi Hospital
- Brief Summary
The purpose of this study was to investigate whether general anesthesia will affect the postoperative recurrence and metastasis of malignant tumor.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- All
- Target Recruitment
- 300
Inclusion Criteria
- ASA I - III Primary liver cancer tumor is single and diameter is less than 3 centimeter There is no major vascular invasion phenomenon, no lymph nodes or extrahepatic metastases The Child - Pugh belong to type A or type B
Exclusion Criteria
- Had a history of liver surgery (including radiofrequency ablation) Severe disease of heart, lung, kidney, the immune system INR > 1.5 or platelet count is less than 45000 cells/mm3 History of opioid addiction Metastatic liver tumors Not sure of primary liver cancer Don't agree to participate in this experiment
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Number of participants with tumor recurrence and metastasis 3 years Follow-up of patients with tumor recurrence and metastasis after Radiofrequency ablation to 3 years
- Secondary Outcome Measures
Name Time Method
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
What molecular mechanisms link general anesthesia to tumor recurrence and metastasis in cancer patients?
How does general anesthesia compare to local anesthesia in reducing postoperative cancer recurrence rates?
Are there specific biomarkers that predict cancer patients' response to anesthesia types in metastasis prevention?
What are the potential adverse events associated with general anesthesia in cancer surgery and their management?
What combination therapies or alternative anesthetic approaches show promise in mitigating tumor recurrence post-surgery?
Trial Locations
- Locations (1)
Shanghai Renji Hospital
🇨🇳Shanghai, Shanghai, China
Shanghai Renji Hospital🇨🇳Shanghai, Shanghai, China