An open labeled single arm clinical trial on the Efficacy of Pankajakasthuri Migraine Oil in migraine

Migraine is a prevalent and debilitating neurological disorder characterized by recurrent attacks of moderate to severe headache, often accompanied by nausea, vomiting, and sensitivity to light and sound. This condition not only impairs individual quality of life but also contributes to significant healthcare burdens globally. Current treatments, primarily analgesics and triptans, can result in adverse effects and are not universally effective. This study aims to evaluate the efficacy of Pankajakasthuri Migraine Oil, an Ayurvedic formulation, in managing migraine without aura. A total of 40 subjects diagnosed with migraine without aura will be recruited from the outpatient department (OPD) of Pankajakasthuri Ayurveda Medical College and Hospital in Kattakada, Thiruvananthapuram. Participants will receive Pankajakasthuri Migraine Oil for six months, with assessments based on the severity, duration, and frequency of migraine attacks, as well as accompanying symptoms such as nausea, photophobia, and phonophobia. Quality of life will also be evaluated using established metrics.