Prevention and Early Detection and Intervention of Post-Coronary Artery Bypass Grafting Surgery (CABG) Acute Kidney Injury (AKI)
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- Mayo Clinic
- 入组人数
- 2,300
- 试验地点
- 1
- 主要终点
- Perfusion pressures (mean arterial pressure) ≥ 65-70 mmHg
研究概览
简要总结
Nephrology participation in care of patients undergoing CABG could reduce AKI through correction of modifiable risk factors and early detection and intervention of post-op AKI.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Adult patients (Age >18 years)
- •Elective CABG at Mayo Clinic Rochester and Shanghai Zhongshan Hospital from 7/1/2016 to 6/30/2017
排除标准
- •Non-elective CABG
- •Renal failure on dialysis
- •Renal transplantation
研究组 & 干预措施
Standard of Care
If participants are randomized into the non-intervention group, the participants' information during the study period will be collected. Participants will be managed by a care provider as per the standard of care. Participants may receive nephrology consultation as indicated clinically.
Standard of Care plus Nephrology Care
If participants are randomized into the intervention group, participants' information will be checked by the study investigators daily for 7 days (2 days pre-op and 5 days post-op). When appropriate, investigators may give suggestions to minimize the participants' risk(s) for AKI. Participant's primary care providers may take the suggestions into consideration. Participants' primary care providers are not obligated to carry out the suggestions that are given.
干预措施: Standard of Care plus Nephrology Care (Procedure)
结局指标
主要结局
Perfusion pressures (mean arterial pressure) ≥ 65-70 mmHg
时间窗: baseline to 5 days
次要结局
未报告次要终点