Effects of Chair-Based Exercise Training on Exercise Capacity in Patients With Acute Exacerbation of COPD

Not Applicable

Completed

• Conditions: Acute Exacerbation of COPD
• Interventions: Other: Control group, Breathing exercise; Other: Treatment group, Chair-Based Exercise Training

• Registration Number: NCT05563493
• Lead Sponsor: Necmettin Erbakan University

Brief Summary

Chronic obstructive pulmonary disease (COPD) is the leading cause of morbidity and mortality worldwide, a respiratory disease characterized by chronic airflow limitation that is not completely reversible.

Impaired pulmonary functions, decreased exercise capacity and quality of life and increased dyspnea perception is prevalent in patients with acute exacerbations of COPD.It was demonstrated exercise training has beneficial effects in patients with acute exacerbations of COPD.

The purpose of this study to evaluate the effects of chair-based exercise training on exercise capacity, respiratory functions, dyspnea, balance, depression anxiety and quality of life in COPD patients in acute exacerbation.

Detailed Description

Acute exacerbations of COPD are generally defined as events in the natural course of the disease characterized by a change in the patient's initial dyspnea, cough or sputum beyond normal daily variations. The main consequences of COPD in acute exacerbation are increased mortality, deterioration in health-related quality of life, faster decline in lung function, marked reduction in physical activity and worsening of peripheral muscle weakness, which have a direct impact on patients' health. Although exacerbations are diagnosed based on respiratory symptoms, there is evidence that they have systemic consequences, including a detrimental effect on skeletal muscle function, exercise tolerance and quality of life.

Chair-based exercise training is defined as a structured and progressive exercise program applied by trainers that provides stability using a chair, which is a part of exercise training for the elderly. It is thought that it would be beneficial to study such an exercise program, since COPD patients in acute exacerbation have less mobilization during hospitalization.

In a limited number of studies, some inconsistencies were observed in the exercises of patients with acute exacerbation of COPD. Studies can therefore now focus on investigating comparisons between different intervention lengths, session durations and frequencies, and intensities of exercise training. For this reason, in our planned study, we will investigate the effects of chair-based exercise training in COPD patients in acute exacerbation. There is no study in the literature investigating the effects of chair-based exercise training in COPD patients in acute exacerbation. For this reason, our study will provide important information support to the literature.

Study Timeline

• Study Start: 2022-08-20
• Status Verified: 2022-09
• Study First Submitted: 2022-09-26
• Study First Submitted QC: 2022-09-29
• Study First Posted: 2022-10-03
• Primary Completion: 2023-05-31
• Study Completion: 2023-06-30
• Last Update Submitted: 2024-02-06
• Last Update Posted: 2024-02-07

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 30

Inclusion Criteria

• Patients who were hospitalized due to acute exacerbation of COPD

Exclusion Criteria

• Patients with orthopedic or neurological problems that may interfere with assessment and education,
• Uncooperative patients,
• Patients with advanced heart problems such as acute coronary syndrome, stable angina pectoris, severe arrhythmias (Atrial fibrillation etc.), decompensated heart failure.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Control group, Breathing exercise	Control group, Breathing exercise	Control group will receive breathing exercises.
Treatment group, Chair-Based Exercise Training	Treatment group, Chair-Based Exercise Training	Treatment group will receive chair-based exercise training. Chair-based exercise training consisting of 20 different exercises will be applied in 2-3 sets with an average of 8-15 repetitions. Rest between sets will average 45-60 seconds.

Primary Outcome Measures

Name	Time	Method
Functional Exercise Capacity	Seven day	Functional exercise capacity will be evaluated with 6-minute walk test.
Pulmonary Function Test	Seven day	This test was evaluated using a spirometry by which is evaluated dynamic lung functions expressed as percentages of expected values.

Secondary Outcome Measures

Name	Time	Method
Timed Up and Go Test	Seven day	The Timed Up and Go test is evaluated dynamic balance.
Depression and Anxiety	Seven day	Evaluated using Hospital Anxiety and Depression Scale (Turkish versions of all scales)
Dyspnea	Seven day	The severity of dyspnea during daily living activities is evaluated using the Modified Medical Research Council (MMRC) dyspnea scale.
One Minute Sit to Stand Test	Seven day	The number of completed sit to stand repetitions in 1 minute. Patients stand/sit from a chair as many times as they can in one minute.
Life of quality	Seven day	Saint George's Respiratory Questionnaire (SGRQ) (Turkish versions of all scales) is used to assess the quality of life of COPD patients.

Trial Locations

Locations (1)

Necmettin Erbakan University Nezahat Keleşoğlu Faculty of Health Sciences; 🇹🇷 Konya, Turkey