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Clinical Trials/NCT05563493
NCT05563493
Completed
Not Applicable

Comparison of the Effects of Chair-Based Exercise Training on Respiratory Functions, Exercise Capacity and Quality of Life in Patients With Acute Exacerbation of Chronic Obstructive Pulmonary Disease

Necmettin Erbakan University1 site in 1 country30 target enrollmentAugust 20, 2022

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Acute Exacerbation of COPD
Sponsor
Necmettin Erbakan University
Enrollment
30
Locations
1
Primary Endpoint
Functional Exercise Capacity
Status
Completed
Last Updated
2 years ago

Overview

Brief Summary

Chronic obstructive pulmonary disease (COPD) is the leading cause of morbidity and mortality worldwide, a respiratory disease characterized by chronic airflow limitation that is not completely reversible.

Impaired pulmonary functions, decreased exercise capacity and quality of life and increased dyspnea perception is prevalent in patients with acute exacerbations of COPD.It was demonstrated exercise training has beneficial effects in patients with acute exacerbations of COPD.

The purpose of this study to evaluate the effects of chair-based exercise training on exercise capacity, respiratory functions, dyspnea, balance, depression anxiety and quality of life in COPD patients in acute exacerbation.

Detailed Description

Acute exacerbations of COPD are generally defined as events in the natural course of the disease characterized by a change in the patient's initial dyspnea, cough or sputum beyond normal daily variations. The main consequences of COPD in acute exacerbation are increased mortality, deterioration in health-related quality of life, faster decline in lung function, marked reduction in physical activity and worsening of peripheral muscle weakness, which have a direct impact on patients' health. Although exacerbations are diagnosed based on respiratory symptoms, there is evidence that they have systemic consequences, including a detrimental effect on skeletal muscle function, exercise tolerance and quality of life. Chair-based exercise training is defined as a structured and progressive exercise program applied by trainers that provides stability using a chair, which is a part of exercise training for the elderly. It is thought that it would be beneficial to study such an exercise program, since COPD patients in acute exacerbation have less mobilization during hospitalization. In a limited number of studies, some inconsistencies were observed in the exercises of patients with acute exacerbation of COPD. Studies can therefore now focus on investigating comparisons between different intervention lengths, session durations and frequencies, and intensities of exercise training. For this reason, in our planned study, we will investigate the effects of chair-based exercise training in COPD patients in acute exacerbation. There is no study in the literature investigating the effects of chair-based exercise training in COPD patients in acute exacerbation. For this reason, our study will provide important information support to the literature.

Registry
clinicaltrials.gov
Start Date
August 20, 2022
End Date
June 30, 2023
Last Updated
2 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Zeynep Pelin Dündar

Research Assistant

Necmettin Erbakan University

Eligibility Criteria

Inclusion Criteria

  • Patients who were hospitalized due to acute exacerbation of COPD

Exclusion Criteria

  • Patients with orthopedic or neurological problems that may interfere with assessment and education,
  • Uncooperative patients,
  • Patients with advanced heart problems such as acute coronary syndrome, stable angina pectoris, severe arrhythmias (Atrial fibrillation etc.), decompensated heart failure.

Outcomes

Primary Outcomes

Functional Exercise Capacity

Time Frame: Seven day

Functional exercise capacity will be evaluated with 6-minute walk test.

Pulmonary Function Test

Time Frame: Seven day

This test was evaluated using a spirometry by which is evaluated dynamic lung functions expressed as percentages of expected values.

Secondary Outcomes

  • Timed Up and Go Test(Seven day)
  • Depression and Anxiety(Seven day)
  • Dyspnea(Seven day)
  • One Minute Sit to Stand Test(Seven day)
  • Life of quality(Seven day)

Study Sites (1)

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