Comparison of outcomes of subtenon Mitomycin C injection Versus soaked sponges mitomycin C application in Deep Sclerectomy.

Phase 3

• Conditions: Open Angle Glaucoma.; Open-angle glaucoma; H40.1

• Registration Number: IRCT20161218031450N5
• Lead Sponsor: Tabriz University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 30 August 2021

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 40

Inclusion Criteria

Patients with open-angle glaucoma (OAG) with advanced caping and progressive visual field defects
A patient with open-angle glaucoma (OAG) who needs medication to control IOP but does not tolerate medication
Patients with open-angle glaucoma (OAG) whose IOP is not well controlled despite medication.
Patients with open-angle glaucoma (OAG) who need multiple medications to control IOP
Willingness to participate in the study (patients with informed consent)

Exclusion Criteria

Lack of proper access to the patient for long-term follow-up
Patients with any congenital abnormality of the anterior chamber angle
Patients with ocular infections
Patients with a history of ocular surgery
Patients with uveitis
Patients with corneal diseases that can affect IOP or measure it (corneal opacity, large pterygium, etc.).
Patients with diabetes and hypertension
Patients with neovascular glaucoma
In case of any ocular or systemic complications, patients are excluded from the study

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Intraocular pressure. Timepoint: Before surgery (one day, 2 weeks, 1 month, 2 months, 3 months, 6 months, after surgery). Method of measurement: Using a Goldman tonometer.

Secondary Outcome Measures

Name	Time	Method
Bleb apperance. Timepoint: 2 months, 3 months, 6 months after surgery. Method of measurement: IBAG(indiana Bleb Grading Scale).