A clinical trial to study the effectiveness of ââ?¬Å?Generalization of Rubricsââ?¬? in treating Typhoid fever

Not Applicable

• Conditions: Health Condition 1: 3- AdministrationHealth Condition 2: A010- Typhoid fever

• Registration Number: CTRI/2022/09/045665
• Lead Sponsor: DR M SATISH KRISHNA

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 17 October 2022

Recruitment & Eligibility

• Status: ot Yet Recruiting
• Sex: Not specified
• Target Recruitment: 0

Inclusion Criteria

Individuals between ages 12 to 60 years of age comprising both genders

Diagnosed Cases of Typhoid fever with clinical symptoms and Rapid dot EIA test or widal positive results

Temperatures between 99F to 104F

Participants with informed consent

Participants who are mentally sound and who can express their sufferings

Exclusion Criteria

Patients with severe Dehydration

Those febrile patients who had received antibiotic treatment for their symptom within 4 days prior to coming to the hospital OPD

Those who were diagnosed for other known febrile illness like malaria haemorragic fevers fevers of viral etiology etc

Known cases of Typhoid fever where the subject has a history of cardiac disorders peptic or gastric ulcerations convulsions and any other major complications

Pregnant women Children with underlying malnutrition and those infected with multidrug resistant isolates

Known cases with history of other bleeding disorders

Diagnosed cases of Typhoid fever with inflammation of pericardium myocardium or to pancreas

Participants who are deaf and dumb or those who cannot express or narrate the symptoms feelings or sufferings

Withdrawal criteria

If improvement is not present within 7 days case shall be referred

Cases going into complications like uncontrolled abdominal pain abdominal guarding not responding to treatment intestinal perforation shall be referred

Non responding cases of delirium.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Typhoid fever is completely reduced - Even in conditions where relevant rubrics are absent to the symptoms elicitedTimepoint: 14days

Secondary Outcome Measures

Name	Time	Method
General feeling of well beingTimepoint: 14days