Comparing Oral and Sublingual Ketamine Lozenges as Rescue Analgesics in Adults with Acute Pai

Phase 2

Completed

• Conditions: Acute Pain; Anaesthesiology - Pain management

• Registration Number: ACTRN12621000240842
• Lead Sponsor: niversity of Western Australia

Brief Summary

Ketamine given sublingually and orally produced similar analgesic effects. Sublingual ketamine has faster onset of action and possibly higher rate of adverse effects.

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Completion: 2011-12-08
• Study Start: 2021-03-08
• Last Update Posted: 16 March 2021

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 30

Inclusion Criteria

1) 18years old or above
2) Inpatients with acute breakthrough pain of 5 or more on numerical rating scale who required additional medication and previously responded to sublingual ketamine.
3) able to self-assess pain scores on NRS

Exclusion Criteria

Patients with known contraindications to ketamine such as: allergy to ketamine; severe cardiovascular disease; history of stroke or cerebral trauma; significant liver disease.

Pregnant women or breastfeeding mothers.

Study & Design

• Study Type: Interventional
• Study Design: Not specified