Pilot trial to compare 24 hour antibiotic regimen with standard 7 day antibiotic regimen for prophylaxis in renal transplant recipients.

Not yet recruiting

• Conditions: Chronic kidney disease, stage 5,

• Registration Number: CTRI/2020/07/026868
• Lead Sponsor: All India Institute Of Medical Sciences New Delhi

Brief Summary

Antibiotic over use and misuse has led to widespread resistance to antibiotics. The study is aimed at comparing 24 hour prophylactic antibiotic against standard 7 day antibiotic prophylaxis in renal transplant recipients. The recipients will be allocated in to the two groups by permuted block randomisation.  Incidence of SSI in the postoperative period in kidney transplant patients as defined by CDC that is 30 day follow up period in both the groups, UTI, chest infections, central venous catheter related infection will be studied and compared. This will help us to gather preliminary data to establish a relevant antibiotic protocol in renal transplant recipients.

Detailed Description

Not available

Study Timeline

• Last Update Posted: 2020-07-20
• Study Start: 2020-09-14

Recruitment & Eligibility

• Status: Not Yet Recruiting
• Sex: All
• Target Recruitment: 50

Inclusion Criteria

• 1.All Renal transplant recipients except those with cadaveric renal grafts.
• 2.Patient is able to follow instructions 3.Patients are ready for regular follow up 4.Able to provide informed written consent.

Exclusion Criteria

• Cadaveric renal grafts.
• Non-compliance with medical care or follow up.
• Patient suffering from psychiatry problems.
• Unable to give consent or patient refusal.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Incidence of SSI in the postoperative period in kidney transplant patients as defined by CDC that is 30 day follow up period in both the groups, UTI, chest infections, central venous catheter related infection.	1 week, 2 weeks and 4 weeks.

Secondary Outcome Measures

Name	Time	Method
Duration of hospital stay, side effects, graft kidney function.	1 week, 2 weeks and 4 weeks.

Trial Locations

Locations (1)

All India Institute Of Medical Sciences; 🇮🇳 Delhi, DELHI, India

All India Institute Of Medical Sciences

🇮🇳Delhi, DELHI, India

Prasanna Ramana A

Principal investigator

9742712903

prasannaramana326@gmail.com