To compare 24 hour versus standard 7 day prophylactic antibiotic regimen in renal transplant recipients: A pilot prospective randomised control study.
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 50
- 试验地点
- 1
- 主要终点
- Incidence of SSI in the postoperative period in kidney transplant patients as defined by CDC that is 30 day follow up period in both the groups, UTI, chest infections, central venous catheter related infection.
研究概览
简要总结
Antibiotic over use and misuse has led to widespread resistance to antibiotics. The study is aimed at comparing 24 hour prophylactic antibiotic against standard 7 day antibiotic prophylaxis in renal transplant recipients. The recipients will be allocated in to the two groups by permuted block randomisation. Incidence of SSI in the postoperative period in kidney transplant patients as defined by CDC that is 30 day follow up period in both the groups, UTI, chest infections, central venous catheter related infection will be studied and compared. This will help us to gather preliminary data to establish a relevant antibiotic protocol in renal transplant recipients.
研究设计
- 研究类型
- Interventional
- 分配方式
- Permuted block randomization, fixed
- 盲法
- Participant Blinded
入排标准
- 年龄范围
- 5.00 Year(s) 至 99.00 Year(s)（—）
- 性别
- All
入选标准
- •1.All Renal transplant recipients except those with cadaveric renal grafts.
- •2.Patient is able to follow instructions 3.Patients are ready for regular follow up 4.Able to provide informed written consent.
排除标准
- •Cadaveric renal grafts.
- •Non-compliance with medical care or follow up.
- •Patient suffering from psychiatry problems.
- •Unable to give consent or patient refusal.
结局指标
主要结局
Incidence of SSI in the postoperative period in kidney transplant patients as defined by CDC that is 30 day follow up period in both the groups, UTI, chest infections, central venous catheter related infection.
时间窗: 1 week, 2 weeks and 4 weeks.
次要结局
- Duration of hospital stay, side effects, graft kidney function.(1 week, 2 weeks and 4 weeks.)