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Clinical Trials/NCT04651816
NCT04651816
Completed
Not Applicable

Penn State Health (PSH) Diabetes Prevention Program (DPP) Pilot

Penn State University1 site in 1 country30 target enrollmentMay 25, 2021
ConditionsPre-diabetes

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Pre-diabetes
Sponsor
Penn State University
Enrollment
30
Locations
1
Primary Endpoint
Subject Retention
Status
Completed
Last Updated
2 years ago

Overview

Brief Summary

This initiative, which is a partnership between State College area Penn State Health ambulatory care clinics located off campus in the State College area, has two primary goals: 1) improve the health and quality of life of Penn State Health patients with pre-diabetes and 2) decrease associated health care costs due to type 2 diabetes and its complications. The results from the study may serve as a model for additional chronic disease prevention programs to implement in additional Penn State Health clinics in the future.

Detailed Description

Through this initiative, providers in Penn State Health ambulatory health care clinics (PSH clinics) will identify pre-diabetic patients to take part in a Diabetes Prevention Program (DPP), modeled after the Centers for Disease Control's (CDC) program. The DPP is a CDC-recognized lifestyle change program developed specifically to prevent type 2 diabetes. It is designed for people who have prediabetes or are at risk for type 2 diabetes, but who do not already have diabetes. We will be using the DPP distance learning program which allows online delivery of classes. A trained lifestyle coach leads the program to help subjects change certain aspects of their lifestyle, like eating healthier, reducing stress, and getting more physically activity. The program also includes group support. The DPP is a year-long program focused on long-term changes and lasting results. Key components of the program include a CDC-approved curriculum with lessons, handouts, and other resources; a lifestyle coach, specifically trained to lead the program; and a support group of people with similar goals and challenges. To that end, this study has multiple arms that will test whether participation in the PSH DPP - and exposure to motivational messages that encourage physical activity or participation in lotteries, an increasingly common strategy for behavioral motivation, - significantly improves program retention and health-related outcomes, compared to those who only participate in the PSH DPP.

Registry
clinicaltrials.gov
Start Date
May 25, 2021
End Date
August 8, 2023
Last Updated
2 years ago
Study Type
Interventional
Study Design
Factorial
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Dennis P. Scanlon

Distinguished Professor of Health Policy and Administration, Director of the Center for Health Care and Policy Research

Penn State University

Eligibility Criteria

Inclusion Criteria

  • Be at least 18 years old and under age 65 AND
  • Body Mass Index ≥25 kg/m2 (≥23 kg/m2 if Asian) AND
  • Not be pregnant at time of enrollment AND
  • Have no previous diagnosis of type 1 or type 2 diabetes AND
  • Have a blood test result in the prediabetes range within the past year, meeting one of these specifications:
  • Hemoglobin A1c: 5.7-6.4%, OR
  • Fasting plasma glucose : 100-125 mg/dL, OR
  • Two-hour plasma glucose (after a 75-gm glucose load): 140-199 mg/dL, OR
  • Have a previous clinical diagnosis of gestational diabetes mellitus (GDM), AND
  • Not in hypertensive crisis with systolic over 180 and/or diastolic over 120

Exclusion Criteria

  • Under 18 years old and over age 65
  • Body Mass Index \<25 kg/m2 (\<23 kg/m2 if Asian)
  • Pregnant at the time of enrollment
  • Previous diagnosis of type 1 or type 2 diabetes
  • Have a blood test result within the past year meeting one of these specifications:
  • Hemoglobin A1c: not in range of 5.7-6.4%
  • Fasting plasma glucose: not in range of 100-125 mg/dL
  • Two-hour plasma glucose (after a 75-gm glucose load): not in range of 140-199 mg/dL
  • No previous clinical diagnosis of gestational diabetes
  • Active hypertensive crisis with systolic over 180 and/or diastolic over 120 (patients in this category would be referred to primary care provider for immediate visit)

Outcomes

Primary Outcomes

Subject Retention

Time Frame: 12 months

Participants will be tracked for retention throughout the study.

Weight Loss

Time Frame: 12 months

Patients will be monitored through out the study for healthy weight loss.

Secondary Outcomes

  • Total Cholesterol(12 months)
  • Blood Pressure(12 months)
  • Pregnancy Status(12 months)
  • Knee Injury and Osteoarthritis Outcome Score (KOOS)(12 months)
  • Opinions about PSH DPP program(12 months)
  • A1c(12 months)
  • Quality of Life (SF-36)(12 months)

Study Sites (1)

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