Clinical profile and outcome in children with Acute Encephalitis Syndrome (AES) -a prospective study
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- NA
- 入组人数
- 154
- 试验地点
- 1
- 主要终点
- 1.Vision
研究概览
简要总结
Acute Encephalitis syndrome (AES ) posses a great public in India occurring both epidemics and sporadically .Although JE was know to be main cause of AES in India and was often paralleled with AES, studies conducted shows a shift in perception of etiology of AES in INDIA which is vey wide and often the cause reminds unknown . This is prospective observational study to be conducted in Kasturba Hospital ,Manipal.All cases admitted with symptoms suggestive of AES will be included in the study after application of inclusion and exclusion criteria .Detailed clinical examination and investigations done as a part of standard care will be documented, entered in predetermined proforma .Details of treatment and hospital course will be included and outcome will be measured at the discharge and at 3 month follow up.
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 1.00 Month(s) 至 18.00 Year(s)(—)
- 性别
- All
入选标准
- •All children 1 month to 18 yrs old diagnosed with Acute Encephalitis Syndrome in Kasturba hospital,Manipal.
排除标准
- •Toxic Encephalopathy 2.Hypertensive Encephalopathy 3.Major congenital anamoliespredisposing to infection .Eg Spina bifida,Meningocele,CSF Rhinorrhoea 4.History of head injury 5Inborn Errors of metabolism.
结局指标
主要结局
1.Vision
时间窗: Outcome assessed at discharge and at first follow up in 3 months
2.Hearing
时间窗: Outcome assessed at discharge and at first follow up in 3 months
5.Neurodeficits
时间窗: Outcome assessed at discharge and at first follow up in 3 months
4.Glasgow coma scale
时间窗: Outcome assessed at discharge and at first follow up in 3 months
3.Seizures
时间窗: Outcome assessed at discharge and at first follow up in 3 months
6.Discharged /Death
时间窗: Outcome assessed at discharge and at first follow up in 3 months
次要结局
未报告次要终点
