SupPoRtive Exercise Programmes for Accelerating REcovery after major ABdominal Cancer surgery (PREPARE-ABC) – A multicentre, 3 arm, parallel randomised controlled trial of standard care alone versus standard care plus supervised hospital based exercise and standard care plus supported home-based exercise pre and post hospital discharge in cancer patients awaiting curative colorectal cancer surgery

orfolk and Norwich University Hospitals NHS Foundation Trust0 个研究点目标入组 1,146 人开始时间: 2016年7月7日最近更新: 2023年12月19日

适应症

试验速览

2021 Protocol article in https://pubmed.ncbi.nlm.nih.gov/34245094 (added 01/11/2021)

•1. Male and female participants = 18 years old
•2. Awaiting a curative elective colorectal resection for cancer
•3. American Society of Anaesthesiologists physical status I-III (ASA, 2014)
•4. Able and willing to provide informed consent
•5. Understand verbal and written instructions in English
•6. Patients who are already participating (or have participated) in other trials may be eligible, but this must be agreed in advance by the relevant trial teams

•1. Contra-indications to exercise (e.g. lower limb amputation without prosthesis, orthopaedic disorder exacerbated by exercise, chronic lung disease causing desaturation with exercise or shortness of breath at rest, severe psychiatric health problems)
•2. Cardiovascular contraindications (e.g. unstable angina, acute left ventricular failure, uncontrolled cardiac arrhythmias, uncontrolled hypertension, cardiac event in the previous 6 weeks, cerebral vascular disease resulting in transient ischaemic attacks)
•3. Participation in other treatment trials, where this has not been agreed in advance with both trial teams

发起方