Replacing some of the starch in the diet with fibre to manage blood glucose levels in those with type 2 diabetes.
Not Applicable
Completed
- Conditions
- Type 2 diabetesNutritional, Metabolic, Endocrine
- Registration Number
- ISRCTN14165221
- Lead Sponsor
- niversity of Surrey
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 20
Inclusion Criteria
1. Patients with a diagnosis of type 2 diabetes > 6 months,
2. Males and females,
3. 18-70yrs,
4. Access to a kitchen,
5. Ability to understand English (to provide informed consent).
Exclusion Criteria
1. Use of insulin and GLP-1 analogues,
2. History of gastroperesis or gastric surgery,
3. Coeliac disease/wheat intolerance,
4. Irritable bowel syndrome,
5. HbA1c >75 mmol/mol,
6. Pregnancy/breast-feeding,
7. Excess alcohol intake,
8. Glucose-lowering drug dosage adjustment within the previous month.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Postprandial glucose (MAGE) excursion resulting from consumption of both diets. The MAGE calculation will be made by measuring the arithmetic mean of the difference between consecutive peaks and nadirs. Blood glucose will be measured continuously, however time points of interest are: 8.15am-9.00am (post breakfast), 10.30am-11.15am (post snacks), 12pm-12.45pm (post lunch), 6.00pm-6.45pm (post dinner).
- Secondary Outcome Measures
Name Time Method <br> 1. Peak postprandial glucose excursion after meals<br> 2. The time to peak postprandial glucose excursion<br> 3. Mean blood glucose<br> 4. The standard deviation of blood glucose<br> 5. 24-hour glucose area under the curve (AUC).<br> Blood glucose will be measured continuously, however time points of interest are: 8.15am-9.00am (post breakfast), 10.30am-11.15am (post snacks), 12pm-12.45pm (post lunch), 6.00pm-6.45pm (post dinner).<br>