The Importance of Needle Gauge for Pain During Injection of Local Anaesthetic

Not Applicable

Completed

• Conditions: Needlestick Injuries
• Interventions: Procedure: Large needle gauge lidocaine injection; Procedure: Normal needle gauge lidocaine injection; Procedure: Small needle gauge lidocaine injection

• Registration Number: NCT02107729
• Lead Sponsor: Norwegian University of Science and Technology

Brief Summary

This study will investigate the influence of needle gauge on pain during injection of local anaesthetic. Healthy volunteers will be recruited, who will each receive three injections with either 21G, 23G or 27G subcutaneously on the abdomen. After each injection, the participants will be asked to evaluate the pain on a Visual analog scale (0-100 mm). It is anticipated that the pain will decrease with decreasing thickness of the needle. The aim of this study is to find a simple method for pain reduction that can be used in clinical practice.

Detailed Description

Not available

Study Timeline

• Study Start: 2014-02
• Study First Submitted: 2014-04-04
• Study First Submitted QC: 2014-04-04
• Study First Posted: 2014-04-08
• Primary Completion: 2014-06
• Study Completion: 2014-06
• Status Verified: 2016-07
• Last Update Submitted: 2016-07-28
• Last Update Posted: 2016-07-29

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 36

Inclusion Criteria

• Age 18-65 years

Exclusion Criteria

• Kidney, heart or liver disease
• Eczema or psoriasis on injection site
• Neuropathy
• Regular use of painkillers
• Hypersensitivity of Lidocaine
• Pregnancy
• Diabetes

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: CROSSOVER

Arm && Interventions

Group	Intervention	Description
Needle gauge normal	Large needle gauge lidocaine injection	injection needle 25 G
Needle gauge large	Normal needle gauge lidocaine injection	injection needle 27 G
Needle gauge small	Large needle gauge lidocaine injection	injection needle 23 G
Needle gauge small	Normal needle gauge lidocaine injection	injection needle 23 G
Needle gauge normal	Normal needle gauge lidocaine injection	injection needle 25 G
Needle gauge large	Small needle gauge lidocaine injection	injection needle 27 G
Needle gauge small	Small needle gauge lidocaine injection	injection needle 23 G
Needle gauge normal	Small needle gauge lidocaine injection	injection needle 25 G
Needle gauge large	Large needle gauge lidocaine injection	injection needle 27 G

Primary Outcome Measures

Name	Time	Method
Pain	60 seconds	1. Visual analog scale; 2. Questionnaire

Trial Locations

Locations (1)

Department of Neuroscience, NTNU; 🇳🇴 Trondheim, Norway