Treatment With Spinal Cord Stimulation: Effect on Sensory Parameters
- Conditions
- Chronic Pain
- Interventions
- Device: Active SCSDevice: Deactivated
- Registration Number
- NCT01261468
- Lead Sponsor
- Danish Pain Research Center
- Brief Summary
The primary purpose is to study the effect of spinal cord stimulation (SCS) on sensory parameters, using quantitative sensory testing (QST).
Patients with established SCS treatment will be examined with QST. Subjects will be randomized to have their SCS device turned off or kept active (1:1) for a 12-hour period, then be reexamined using the same QST protocol.
After the 2nd examination all patients cross over (ie. inactive devices are activated, active devices are deactivated) and are reexamined after a new 12-hour period.
The investigators expect to demonstrate that SCS treatment has a significant effect on sensory parameters associated with pain hypersensitivity but no significant effect on sensory parameters associated with detection of non-painful stimuli.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 15
- minimum age 18
- able to understand participant information and cooperate at the neurological examination
- uncomplicated treatment with spinal cord stimulation for at least 3 months
- pain in only one extremity
- treatment effect in only one extremity
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- CROSSOVER
- Arm && Interventions
Group Intervention Description Active SCS Active SCS - Inactive SCS Deactivated -
- Primary Outcome Measures
Name Time Method Change in sensory parameters 24 hours
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Danish Pain Research Center
🇩🇰Aarhus C, Denmark