Changes in the ocular surface parameters after cataract surgery in patients with type 2 diabetes

Not Applicable

Completed

• Conditions: Diseases of the eye and adnexa

• Registration Number: KCT0006960
• Lead Sponsor: Ewha Womans University Medical Center

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Completion: 2020-07-29
• Last Update Posted: 7 February 2022

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 63

Inclusion Criteria

control group : Patients who do not have type 2 diabetes, between 40 and 80 years of age, and who do not meet the other exclusion criteria, and are planning cataract surgery at our medical center.
type 2 diabetes mellitus with no diabetic retinopathy: Among patients with type 2 diabetes who are between 40 and 80 years of age, who do not have diabetic retinopathy and are planning cataract surgery at our medical center.
type 2 diabetes mellitus with diabetic retinopathy: Type 2 diabetes patients aged 40 to less than 80 who have diabetic retinopathy and are planning cataract surgery at our medical center.

Exclusion Criteria

- patients who are taking medications that may affect tear secretion, such as diuretics
- Systemic diseases other than diabetes that may affect the ocular surface (Sjogren's syndrome, hemodialysis, etc.)
- In case of accompanying ocular surface disease such as allergic conjunctivitis, preexisting severe dry eye or meibomian gland dysfunction
- If intravitreal or periocular drug injection has been performed within the last 3 months
- patinets who havelaser corneal resection (LASIK, LASEK, Excimer laser) in the past
- In case of complications related to cataract surgery (posterior capsule rupture, retinal detachment, intraocular lens reoperation due to positional abnormalities, macular edema, etc.)
- If the subject is unable to read and understand the consent form and is unable to voluntarily consent (intelligence
the underprivileged, the elderly, foreigners, illiteracy, etc.)

Study & Design

• Study Type: Observational Study
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Differences in the ocular surface in diabetic patients and normal cataract patients before and after surgery

Secondary Outcome Measures

Name	Time	Method
Differences in cytokines in tears before and after surgery in diabetic and normal cataract patients