CTRI/2026/03/107153尚未招募不适用
Lumateperone as an adjunctive therapy in negative and cognitive symptoms of Schizophrenia: An open label study
Central Institute Of Psychiatry, Ranchi1 个研究点 分布在 1 个国家目标入组 60 人开始时间: 2026年4月16日最近更新:
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 60
- 试验地点
- 1
研究概览
简要总结
Schizophrenia patients with negative and cognitive symptoms will be recruited and divided into 2 groups. one group will receive Tab Lumateperone 42mg OD for 4 weeks and will be clinically assessed using scales like BACS, and compared with baseline. Another group will receive usual treatment and compared with the other group.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- None
入排标准
- 年龄范围
- 18.00 Year(s) 至 60.00 Year(s)（—）
- 性别
- All
入选标准
- •participants satisfying the ICD-11 criteria for schizophrenia 2.illness duration of equal to or more than 2 years
- •patient giving written informed consent
- •score less than or equal to 25 in Hindi Montreal cognitive assessment test
- •PANSS negative symptoms score of equal to or more than 4 or more than 15 combined.
- •SANS score more than 20.
排除标准
- •Any other major comorbid psychiatric diagnosis or significant concurrent medical illness.
- •Patients with organic brain disorder and/or mental retardation.
- •Patients on treatment with medications that can influence cognitive functioning: Anticholinergics (except trihexyphenidyl).
- •Patients who have received ECT in the past 6 months.
- •Contraindications to use of Lumateperone.
研究者
Dr Rishabh Nagar
Central Institute of Psychiatry
研究点 (1)
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