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Clinical Trials/NCT01695564
NCT01695564
Completed
N/A

Comparison of Safety and Efficacy of Left Atrial Appendage Occlusion Devices

Kansas City Heart Rhythm Institute1 site in 1 country169 target enrollmentMay 2012

Overview

Phase
N/A
Intervention
Not specified
Conditions
Atrial Fibrillation
Sponsor
Kansas City Heart Rhythm Institute
Enrollment
169
Locations
1
Primary Endpoint
Effect of LAA occlusion by LARIAT device
Status
Completed
Last Updated
7 years ago

Overview

Brief Summary

Atrial fibrillation (AF) is the most common cardiac rhythm disorder in clinical practice. In the last two decades the number of hospitalizations for AF has increased two- to three-fold. More than 6 million people worldwide suffer from atrial fibrillation (AF), a cardiac disorder that results in systemic emboli. Patients with AF are 5 times more likely to have a stroke compared with those without AF.

This registry will collection information on two devices that are used to treat AF. The WATCHMAN and LARIAT. The differences in techniques and subsequent effects of the two devices on outcomes related to AF has not been studied. This study will look to compare the two devices to see how the outcomes may vary.

Registry
clinicaltrials.gov
Start Date
May 2012
End Date
February 2018
Last Updated
7 years ago
Study Type
Observational
Sex
All

Investigators

Sponsor
Kansas City Heart Rhythm Institute
Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Patients who have had a LARIAT LAA device occlusion

Exclusion Criteria

  • Patients who have PFO/ASD/critical carotid artery (\>70% blockage) disease and hemorrhagic strokes

Outcomes

Primary Outcomes

Effect of LAA occlusion by LARIAT device

Time Frame: Change from Day 0 to 356 post-procedure

This registry will provide data on patient outcomes at different times during follow up.This includes: changes in the appendage size, shape and patients medical history.

Secondary Outcomes

  • Compare effectiveness of LAA occlusion procedure by evaluating LAA jet velocities(Days 0, 90, 180, 365 post-procedure and annually thereafter)

Study Sites (1)

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