ew application of collagen membrane for less invasive procedure of autologous cultured cartilage implantatio
- Conditions
- Full-thickness articular cartilage defects of the knee due to trauma or osteochondritis dissecans
- Registration Number
- JPRN-UMIN000027498
- Lead Sponsor
- Hiroshima University Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 5
Not provided
1. Patient who is diagnosed as oteoarthritis of the knee 2. Patient who is diagnosed or suspected malignant tumor 3. Patient who has complications and considered as inappropriate case by orthopaedic surgeon in charge. 4. Hypersensitive patients against gentamicin, amphotericin B, or amnoglycoside. 5. Hypersensitive patients against intradermal injection of atelocollagen or bovine product. 6. Patient who has allergic reaction to bovine or swine. 7. Patient who is diagnosed as rheumatoid arthritis, psoriatic arthritis, systemic lupus erythematosus, dermatomyositis, polymyositis, autoimmune thyropathy, multiple arteritis, scleroderma, ulcerative colitis, Crohn's disease, Sjogren's syndrome, Reiter's syndrome, mixed connective tissue dissase. 8. Patient who has past history about anaphylactic shock. 9. Patient who has hypersensitive against atelocollagen. 10. Patient who is considered as inappropriate case by orthopaedic surgeon in charge.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Clinical score from Knee Injury and Osteoarthritis Outcome Score (KOOS) sheet obtained at registration, 26 weeks, and 52 weeks after implantation.
- Secondary Outcome Measures
Name Time Method