Cardiovascular Evaluation Before Renal Transplantation

• Conditions: Chronic Kidney Disease; Coronary Artery Disease
• Interventions: Other: diagnostic procedure

• Registration Number: NCT01064674
• Lead Sponsor: University Hospital Muenster

Brief Summary

Due to rising importance of cardiovascular disease before and after renal transplantation we have changed our standard diagnostic procedure and perform stress echocardiography and myocardial scintigraphy. We would like to monitor these results and the outcome of our patients.

Detailed Description

Chronic kidney disease is a well-known risk factor for cardiovascular disease. Patients waiting for a renal transplantation usually undergo an extensive diagnostic procedure to avoid complications after transplantation such as neoplasia or inflammation. In the past years, cardiovascular complications before and after renal transplantation have gained more attention. We therefore have changed our standard diagnostic procedure before renal transplantation and perform stress echocardiography and myocardial scintigraphy. Thus we would like to evaluate our new standard diagnostic procedure and observe the results of these diagnostic procedures as well as their impact on clinical outcome.

Study Timeline

• Study Start: 2009-12
• Status Verified: 2010-01
• Study First Submitted: 2010-02-05
• Study First Submitted QC: 2010-02-05
• Last Update Submitted: 2010-02-05
• Study First Posted: 2010-02-08
• Last Update Posted: 2010-02-08
• Primary Completion: 2010-06
• Study Completion: 2010-09

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 100

Inclusion Criteria

• endstage renal disease
• preparing for renal transplantation

Exclusion Criteria

• children (< 18 years)
• women who are pregnant or nursing
• patients who are also awaiting heart transplantation or have already a heart transplant
• severe mental illness

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
before renal transplantation	diagnostic procedure	Patients with CKD IV° to V° who are actually registering for a renal transplantation in our department.

Primary Outcome Measures

Name	Time	Method
cardiovascular morbidity	one year

Trial Locations

Locations (1)

Department of Internal Medicine D, University Hospital Muenster; 🇩🇪 Muenster, Germany