Reconstructing CT images from MRI scans of the cervical spine: a feasibility and validation study of Bone MRI

• Conditions: bone disease; radiculopathy; 10005959

• Registration Number: NL-OMON46499
• Lead Sponsor: Isala Klinieken

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 15 April 2024

Recruitment & Eligibility

• Status: Pending
• Sex: Not specified
• Target Recruitment: 50

Inclusion Criteria

- Subjects * 50 years old
- Indication for MRI cervical spine
- Eligible for MRI
- Written informed consent
- Able to read in Dutch

Exclusion Criteria

- Not eligible for MRI
- Previous participation in the study
- Pregnancy
- Concomitant participation in a research project in which the patient is exposed to ionizing radiation
- History of osteosynthesis of the cervical spine
- History of (psychiatric) disorder which causes the patient to be incompetent to make a thought-out decision.

Study & Design

• Study Type: Observational non invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Objective and subjective image quality of Bone MRI will be investigated.<br /><br>Geometrical accuracy and voxelwise similarity will be assessed to evaluate<br /><br>objective image quality and will be leading in the acceptance of Bone MRI<br /><br>images. </p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Subjective image scores is our secondary outcome measure. Bone MRI scans will<br /><br>be assessed by two radiologists and one neurosurgeon and should reach a score<br /><br>of 3 or higher (scale 1-4) in 80% in order to be qualified as acceptable, in<br /><br>the rating of predetermined anatomical structures.</p><br>