Management of Noninvasive Ventilation in Hypoxemic Patients

Completed

• Conditions: Noninvasive Ventilation

• Registration Number: NCT03250416
• Lead Sponsor: Chongqing Medical University

Brief Summary

The investigator aimed to manage noninvasive ventilation in patients with hypoxemic respiratory failure.

Detailed Description

Patients with hypoxemic respiratory failure were enrolled in this study. The investigator collected the data at beginning and first stage of noninvasive ventilation to analyze the efficacy of noninvasive ventilation. To manage the noninvasive ventilation easily, the investigator also aimed to develop a scale to predict the efficacy of noninvasive ventilation, and used this scale to guide clinicians how to use noninvasive ventilation.

Study Timeline

• Study First Submitted: 2017-08-11
• Study First Submitted QC: 2017-08-14
• Study First Posted: 2017-08-15
• Study Start: 2017-09-01
• Primary Completion: 2021-09-30
• Study Completion: 2021-09-30
• Status Verified: 2022-07
• Last Update Submitted: 2022-07-05
• Last Update Posted: 2022-07-07

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 2179

Inclusion Criteria

• PaO2/FiO2 less than 300; PaCO2 less than 50 mmHg; Respiratory rate more than 25 breaths/min or presence of labored breath.

Exclusion Criteria

• Requirement of emergency intubation; Sequential use of noninvasive ventilation after extubation;Use of noninvasive ventilation after accident extubation.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Noninvasive ventilation failure	From participation to 30 days	Noninvasive ventilation failure was defined as requirement of intubation.

Secondary Outcome Measures

Name	Time	Method
Mortality	From participation to 30 days	Mortality in ICU and hospital
ICU stay	From participation to 30 days	Length of ICU stay

Trial Locations

Locations (1)

The First Affiliated Hospital ,Chongqing Medical Univercity; 🇨🇳 Chongqing, Chongqing, China