comparing two drugs midazolam and fentanyl used in spinal anesthesia for prolonged pain relief post surgery in patients undergoing caesarean sectio
- Conditions
- Health Condition 1: O- Medical and Surgical
- Registration Number
- CTRI/2023/01/048892
- Lead Sponsor
- Sikkim Manipal Institute of medical sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 0
1.ASA physical status I
2.ASA physical status II
3.Age from 18-35 years
4.Scheduled to undergo elective caesarean section under spinal anesthesia
ASA III or IV patients.
? Patients’ refusal for spinal anesthesia.
? Patients physically dependent on narcotics or benzodiazepine.
? Patients with history of drug allergy to fentanyl and midazolam
? Patients with gross spinal abnormality, localized skin sepsis, haemorrhagic diathesis or neurological involvement/ diseases and any contraindication for spine.
? Head injury cases.
? Patients with cardiac, pulmonary, hepatic or renal disorders.
? Patients with peripheral neuropathy.
? Patients having inadequate sub arachnoid blockade and who are later supplemented by general anesthesia.
? Chronic pain at puncture site.
? Patients who are unable to communicate.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To study and compare the Onset, Duration of Analgesia <br/ ><br>• Consumption of additional Analgesics in first Post-Operative 12 HoursTimepoint: 12 hours
- Secondary Outcome Measures
Name Time Method To study Hemodynamic changes <br/ ><br>• Sedative Effect on Mother (Ramsay sedation score) and on New Born (APGAR Score) <br/ ><br>• Associated adverse effect during the study period (Nausea, Vomiting, shivering, Pruritis, Sedation, Hypotension, Bradycardia Hypersensitive Reaction, Respiratory DepressionTimepoint: 12 hours