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Clinical Trials/NCT05314465
NCT05314465
Completed
Not Applicable

Effectiveness of Neural Mobilization on Spasticity and Upper Limb Function in Individuals With Stroke

Asir John Samuel3 sites in 1 country7 target enrollmentNovember 22, 2021
ConditionsStroke

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Stroke
Sponsor
Asir John Samuel
Enrollment
7
Locations
3
Primary Endpoint
Modified Ashworth Scale (MAS)
Status
Completed
Last Updated
3 years ago

Overview

Brief Summary

Spasticity after stroke is common that affect upper limb strength and make activities of daily living difficult. There are many techniques but not any standardized technique for long term effect on reduction of spasticity and improving upper limb strength. This study aimed to explore and understand the effectiveness of neural mobilization on reduction of spasticity and improving upper limb strength in individuals with stroke. This is mixed method approach of embedded design, multicentric study recruited 7 individuals with stroke as no new themes or codes were emerging (data saturated). Median nerve mobilization was given 20 oscillations per minute for 3 times & repeated 3 times with a pause of 1 minute between each sets for 5times/week for 4weeks. Outcome measures were Modified Ashworth Scale (MAS), Brunnstrom's grading of hand recovery and Hydraulic hand dynamometer(HHD) for grip and pinch strength. Pre and post outcomes data were collected at baseline and 4weeks after intervention and in depth face to face structured interviews was conducted after 4weeks of intervention to explore the effectiveness of median nerve mobilization on reduction of spasticity and the improvement of upper limb strength.

Detailed Description

Spasticity after stroke is common that affect upper limb strength and make activities of daily living difficult. There are many techniques but not any standardized technique for long term effect on reduction of spasticity and improving upper limb strength. This study aimed to explore and understand the effectiveness of neural mobilization on reduction of spasticity and improving upper limb strength in individuals with stroke. This is mixed method approach of embedded design, multicentric study recruited 7 individuals with stroke as no new themes or codes were emerging (data saturated). Median nerve mobilization was given 20 oscillations per minute for 3 times \& repeated 3 times with a pause of 1 minute between each sets for 5times/week for 4weeks. Primary outcome measure was Modified Ashworth Scale (MAS) to assess elbow and wrist flexors spasticity and secondary outcome measures were Brunnstrom's stages for hand recovery and Hydraulic hand dynamometer(HHD) to measure grip and pinch strength. Pre and post outcomes data were collected at baseline and 4weeks after intervention and in depth face to face structured interviews was conducted after 4weeks of intervention to explore the effectiveness of median nerve mobilization on reduction of spasticity and the improvement of upper limb strength.

Registry
clinicaltrials.gov
Start Date
November 22, 2021
End Date
March 15, 2022
Last Updated
3 years ago
Study Type
Interventional
Study Design
Single Group
Sex
All

Investigators

Sponsor
Asir John Samuel
Responsible Party
Sponsor Investigator
Principal Investigator

Asir John Samuel

Professor

Maharishi Markendeswar University (Deemed to be University)

Eligibility Criteria

Inclusion Criteria

  • Participants with subacute and chronic stroke (1month and above) having upper limb spasticity.
  • Participants with haemorrhagic and ischemic stroke.
  • Participants who tolerate the supine position.
  • Participants who are oriented and alert.
  • Both males and females.
  • Participants older than 18 years.

Exclusion Criteria

  • Participants with a score greater than 3 on The Modified Ashworth Scale.
  • Participants with affected speech.
  • Participants with upper limb deformity.
  • Participants experiencing dizziness.
  • Any increase in the dosage of anti-spastic medications during the intervention period.
  • General health problems or pathologies that affect the nervous system like uncontrolled diabetes, hypertension and recent surgeries.
  • Recent onset of worsening neurological signs.

Outcomes

Primary Outcomes

Modified Ashworth Scale (MAS)

Time Frame: Change from baseline and 4 weeks

For spasticity, Total 4 grades are there. Grade 0 means no increase in muscle tone and grade 4 means affected part rigid in flexion or extension. More grade means more spasticity is there.

Secondary Outcomes

  • Brunnstrom's stages for hand recovery(Change from baseline and 4 weeks)
  • Hydraulic hand dynamometer(Change from baseline and 4 weeks)

Study Sites (3)

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