Outcome of Rheumatoid Arthritits patients following adjunct statin therapy
Phase 3
- Conditions
- Health Condition 1: null- Diagnosed Rheumatoid Arthritis patients with active disease
- Registration Number
- CTRI/2014/12/005233
- Lead Sponsor
- Kalinga Institute of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Open to Recruitment
- Sex
- Not specified
- Target Recruitment
- 60
Inclusion Criteria
diagnosed cases of Rheumatoid Arthritis with active disease and under any DMARD therapy
Exclusion Criteria
Patients with history of -
1.Diabetes
2.Renal Disease (due to cause other than RA)
3.intra-articular Cortisone injection within preceding 4 weeks of initial visit
4.active or recent infection
5. alcohol abuse, smoking
6.chronic disease other than RA affecting the Joints
7.Liver disease
8.Pregnancy
9. Breast feeding
10. Allergy to Atorvastatin
11.inclusion in other studies with investigational products
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Clinical- tender joint count, swollen joint count, general health status in VAS, DAS 28 score, HAQ score, CDAI, SDAI <br/ ><br>Biochemical parameter measured by CRP, ESR, MicroalbuminuriaTimepoint: initiation <br/ ><br>1 month <br/ ><br>3 months
- Secondary Outcome Measures
Name Time Method remission or improvementTimepoint: none defined