on-randomized controlled trial assessing the usefulness of new diagnostic and therapeutic algorithms for prolonged cough - NHOM-Cough

Sagamihara National Hospital0 sites500 target enrollmentMarch 23, 2018

ConditionsCough

Overview

No summary available.

Registry

who.int

Start Date

March 23, 2018

End Date

TBD

Last Updated

2 years ago

Study Type

Interventional

Sex

All

Sponsor

Sagamihara National Hospital

•(1\) Confirmed obvious cough improvement naturally or by treatment during the course before visit (2\) Having a history of treatment as asthma including cough asthma within three years besides this episode (3\) Having a history or complications of chronic respiratory/heart/kidney disease, GERD, autoimmune /inflammatory bowel disease, tonsil hypertrophy, or laryngeal disease (4\) Pregnant or possibly pregnant (5\) Having a history of drug irritation or severe side effects to macrolide antibiotics, PPI, ICS, H1 blocker, H2 blocker, or beta stimulant (6\) Confirmed pulmonary shadow abnormality or obvious heart expansion in chest X\-ray (7\) With obvious airway infection symptoms (fever of 37\.5 degree Celsius. or higher or purulent sputum) at the initial visit to the institution (8\) Whose Brinkman Index (average number of smokers per day x total smoking years) is 400 or more (9\) With the rale sound by consultation including mild rales and forced expiration. (To listen carefully to mild twisting sounds in the lower lungs and auscultation with mild wheezing (10\) Using ACE inhibitors (but can enter at 2 weeks or later after discontinuation) (11\) Taking orally H2 blockers, PPI, oral steroids, systemic immunosuppressants or psychotropic drugs for some underlying disease (12\) Others where the attending doctor judged inappropriate to participate in this study