on-randomized controlled trial assessing the usefulness of new diagnostic and therapeutic algorithms for prolonged cough
- Conditions
- Cough
- Registration Number
- JPRN-UMIN000031854
- Lead Sponsor
- Sagamihara National Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- All
- Target Recruitment
- 500
Not provided
(1) Confirmed obvious cough improvement naturally or by treatment during the course before visit (2) Having a history of treatment as asthma including cough asthma within three years besides this episode (3) Having a history or complications of chronic respiratory/heart/kidney disease, GERD, autoimmune /inflammatory bowel disease, tonsil hypertrophy, or laryngeal disease (4) Pregnant or possibly pregnant (5) Having a history of drug irritation or severe side effects to macrolide antibiotics, PPI, ICS, H1 blocker, H2 blocker, or beta stimulant (6) Confirmed pulmonary shadow abnormality or obvious heart expansion in chest X-ray (7) With obvious airway infection symptoms (fever of 37.5 degree Celsius. or higher or purulent sputum) at the initial visit to the institution (8) Whose Brinkman Index (average number of smokers per day x total smoking years) is 400 or more (9) With the rale sound by consultation including mild rales and forced expiration. (To listen carefully to mild twisting sounds in the lower lungs and auscultation with mild wheezing (10) Using ACE inhibitors (but can enter at 2 weeks or later after discontinuation) (11) Taking orally H2 blockers, PPI, oral steroids, systemic immunosuppressants or psychotropic drugs for some underlying disease (12) Others where the attending doctor judged inappropriate to participate in this study
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method